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Details on Person Molecular enzymology of mammalian Delta1-pyrroline-5-carboxylate synthase. Alternative splice donor utilization generates isoforms with different sensitivity to ornithine inhibition

Class:IdLiteratureReference:508038
_displayNameMolecular enzymology of mammalian Delta1-pyrroline-5-carboxylate synthase. Alternative splice donor utilization generates isoforms with different sensitivity to ornithine inhibition
_timestamp2010-02-10 19:21:27
author[Person:70624] Hu, Chien-an A
[Person:70685] Lin, Wei Wen
[Person:70621] Obie, Cassandra
[Person:70630] Valle, David
created[InstanceEdit:508032] D'Eustachio, P, 2010-02-10
journalJ Biol Chem
modified[InstanceEdit:508096] D'Eustachio, P, 2010-02-10
pages6754-62
pubMedIdentifier10037775
titleMolecular enzymology of mammalian Delta1-pyrroline-5-carboxylate synthase. Alternative splice donor utilization generates isoforms with different sensitivity to ornithine inhibition
volume274
year1999
(literatureReference)[CatalystActivityReference:9643295] delta1-pyrroline-5-carboxylate synthetase activity of P5CS dimers [mitochondrial inner membrane] Molecular enzymology of mammalian Delta1-pyrroline-5-carboxylate synthase. Alternative splice donor utilization generates isoforms with different sensitivity to ornithine inhibition
[Reaction:508040] glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] [Homo sapiens]
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