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Details on Person p-STAT5 dimer [nucleoplasm]

Class:Id	Complex:508012
_displayName	p-STAT5 dimer [nucleoplasm]
_timestamp	2012-12-08 09:55:31
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:508009] Jupe, S, 2010-02-10
hasComponent	[DefinedSet:1469978] p-STAT5 [nucleoplasm] [Homo sapiens] [DefinedSet:1469978] p-STAT5 [nucleoplasm] [Homo sapiens]
modified	[InstanceEdit:508027] Jupe, S, 2010-02-10 [InstanceEdit:919403] Jupe, S, 2010-08-04 [InstanceEdit:2752148] May, B, 2012-12-08
name	p-STAT5 dimer
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1109464] R-HSA-508012.1
(activeUnit)	[NegativeGeneExpressionRegulation:8865694] Negative gene expression regulation by '2x(p-STAT5A,p-STAT5B):BRWD1 gene [nucleoplasm]' [PositiveRegulation:8983073] Positive regulation by 'CISH gene, SOCS1 gene, SOCS2 gene:p-STAT5 dimer [nucleoplasm]' [PositiveGeneExpressionRegulation:9978245] Positive gene expression regulation by 'p-STAT5 dimer:IL4R gene [nucleoplasm]'
(hasComponent)	[Complex:8865622] 2x(p-STAT5A,p-STAT5B):BRWD1 gene [nucleoplasm] [Homo sapiens] [Complex:9012668] CISH gene, SOCS1 gene, SOCS2 gene:p-STAT5 dimer [nucleoplasm] [Homo sapiens] [Complex:9020756] p-STAT5 dimer:KPNA4,KPNA5:KPNB1 [nucleoplasm] [Homo sapiens] [Complex:9022296] p-STAT5 dimer:KPNA4,KPNA5 [nucleoplasm] [Homo sapiens] [Complex:9978235] p-STAT5 dimer:IL4R gene [nucleoplasm] [Homo sapiens]
(hasMember)	[CandidateSet:9020796] p-STAT5 dimer dissociates from importin complex [nucleoplasm] [Homo sapiens] [DefinedSet:9674540] p-Y-STAT1,3,5 dimer [nucleoplasm] [Homo sapiens]
(input)	[Reaction:8865626] p-STAT5 dimers bind the BRWD1 gene promoter [Homo sapiens] [BlackBoxEvent:9012671] p-STAT5 binds CISH, SOCS1 and SOCS2 gene [Homo sapiens] [Reaction:9978250] Phosphorylated STAT5 dimer binds the IL4R gene [Homo sapiens]
(output)	[BlackBoxEvent:507937] STAT5 dimers translocate to the nucleus [Homo sapiens] [BlackBoxEvent:9020906] p-STAT5 dimer dissociates from KPNA4:KPNA5:RAN:GTP:CSE1L [Homo sapiens]
(regulator)	[PositiveRegulation:9020809] Positive regulation by 'p-STAT5 dimer [nucleoplasm]'
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No pathways have been reviewed or authored by p-STAT5 dimer [nucleoplasm] (508012)