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Details on Person Interleukin-7 (IL7)-activated Signal transducer and activato...

Class:IdSummation:507992
_displayNameInterleukin-7 (IL7)-activated Signal transducer and activato...
_timestamp2017-10-20 11:15:09
created[InstanceEdit:508009] Jupe, S, 2010-02-10
literatureReference[LiteratureReference:9026557] The IL-7 receptor controls the accessibility of the TCRgamma locus by Stat5 and histone acetylation
[LiteratureReference:9022713] Stat5 mediates the IL-7-induced accessibility of a representative D-Distal VH gene
modified[InstanceEdit:508027] Jupe, S, 2010-02-10
[InstanceEdit:1213499] Jupe, S, 2011-02-11
[InstanceEdit:1364048] Jupe, S, 2011-06-23
[InstanceEdit:8986228] Duenas, Corina, 2017-04-24
[InstanceEdit:9020911] Duenas, Corina, 2017-09-11
[InstanceEdit:9021133] Duenas, Corina, 2017-09-14
[InstanceEdit:9021931] Duenas, Corina, 2017-09-21
[InstanceEdit:9022294] Duenas, Corina, 2017-09-22
[InstanceEdit:9022520] Duenas, Corina, 2017-09-25
[InstanceEdit:9022714] Duenas, Corina, 2017-09-25
[InstanceEdit:9026554] Jupe, Steve, 2017-10-20
textInterleukin-7 (IL7)-activated Signal transducer and activator of transcription 5A or 5B (typically referred to as STAT5) is recruited rapidly to the promoters of IL7-regulated genes (Ye et al. 2001, Stanton & Brodeur 2005).
(summation)[BlackBoxEvent:507937] STAT5 dimers translocate to the nucleus [Homo sapiens]
[BlackBoxEvent:9020906] p-STAT5 dimer dissociates from KPNA4:KPNA5:RAN:GTP:CSE1L [Homo sapiens]
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