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Details on Person The structure of apo human glutamate dehydrogenase details subunit communication and allostery

Class:IdLiteratureReference:507956
_displayNameThe structure of apo human glutamate dehydrogenase details subunit communication and allostery
_timestamp2010-02-09 23:54:43
author[Person:507962] Smith, TJ
[Person:507964] Schmidt, T
[Person:507967] Fang, J
[Person:507963] Wu, J
[Person:507959] Siuzdak, G
[Person:77297] Stanley, CA
created[InstanceEdit:507953] D'Eustachio, P, 2010-02-09
journalJ Mol Biol
modified[InstanceEdit:507968] D'Eustachio, P, 2010-02-09
pages765-77
pubMedIdentifier12054821
titleThe structure of apo human glutamate dehydrogenase details subunit communication and allostery
volume318
year2002
(literatureReference)[Reaction:70589] alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ (GLUD1,2) [Homo sapiens]
[Reaction:70600] glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ (GLUD1,2) [Homo sapiens]
[RegulationReference:9641228] Positive regulation by 'ADP [mitochondrial matrix]' Expression, purification and characterization of human glutamate dehydrogenase (GDH) allosteric regulatory mutations
[RegulationReference:9642935] Negative regulation by 'GTP [mitochondrial matrix]' Expression, purification and characterization of human glutamate dehydrogenase (GDH) allosteric regulatory mutations
[Complex:70583] GLUD hexamer [mitochondrial matrix] [Homo sapiens]
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