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Details on Person STAT5 dimers translocate to the nucleus
Class:Id BlackBoxEvent:507937
_displayName STAT5 dimers translocate to the nucleus
_doRelease TRUE
_timestamp 2020-08-08 06:47:53
authored [InstanceEdit:744679] Ray, KP, 2010-05-17
compartment [Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created [InstanceEdit:507917] Jupe, S, 2010-02-09
edited [InstanceEdit:924611] Jupe, S, 2010-08-06
inferredFrom
input [Complex:507919] p-STAT5 dimer [cytosol] [Homo sapiens]
isChimeric FALSE
literatureReference [LiteratureReference:9022713] Stat5 mediates the IL-7-induced accessibility of a representative D-Distal VH gene [LiteratureReference:9026557] The IL-7 receptor controls the accessibility of the TCRgamma locus by Stat5 and histone acetylation
modified [InstanceEdit:507944] Jupe, S, 2010-02-09 [InstanceEdit:508009] Jupe, S, 2010-02-10 [InstanceEdit:508254] Jupe, S, 2010-02-11 [InstanceEdit:918253] Jupe, S, 2010-08-02 [InstanceEdit:926765] Jupe, S, 2010-08-06 [InstanceEdit:941871] Jupe, S, 2010-09-06 [InstanceEdit:1213499] Jupe, S, 2011-02-11 [InstanceEdit:1233244] Jupe, S, 2011-03-17 [InstanceEdit:1364048] Jupe, S, 2011-06-23 [InstanceEdit:1576229] Jupe, S, 2011-09-07 [InstanceEdit:2752153] May, B, 2012-12-08 [InstanceEdit:9020559] Duenas, Corina, 2017-09-07 [InstanceEdit:9025991] Jupe, Steve, 2017-10-16 [InstanceEdit:9026554] Jupe, Steve, 2017-10-20 [InstanceEdit:9697203] May, Bruce, 2020-08-08 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name STAT5 dimers translocate to the nucleus
output [Complex:508012] p-STAT5 dimer [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate 2010-09-21
reviewed [InstanceEdit:1213492] Villarino, A, 2011-02-11 [InstanceEdit:1233246] Dooms, H, 2011-03-17 [InstanceEdit:1364056] Waters, MJ, 2011-06-23
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:1104150] R-HSA-507937.4
summation [Summation:507992] Interleukin-7 (IL7)-activated Signal transducer and activato...
(hasEvent) [Pathway:512988] Interleukin-3, Interleukin-5 and GM-CSF signaling [Homo sapiens] [Pathway:982772] Growth hormone receptor signaling [Homo sapiens] [Pathway:1266695] Interleukin-7 signaling [Homo sapiens] [Pathway:2586552] Signaling by Leptin [Homo sapiens] [Pathway:9020558] Interleukin-2 signaling [Homo sapiens]
(precedingEvent) [Reaction:8865626] p-STAT5 dimers bind the BRWD1 gene promoter [Homo sapiens] [BlackBoxEvent:9012671] p-STAT5 binds CISH, SOCS1 and SOCS2 gene [Homo sapiens] [BlackBoxEvent:9703436] STAT5-dependent PIM1 gene expression downstream of FLT3 ITD and fusion mutants [Homo sapiens] [Reaction:9978250] Phosphorylated STAT5 dimer binds the IL4R gene [Homo sapiens]
(updatedInstance) [_UpdateTracker:9780257] Update Tracker - [BlackBoxEvent:507937] STAT5 dimers translocate to the nucleus - v63:[add_removeLiteratureReference, modifyText] [_UpdateTracker:9781338] Update Tracker - [BlackBoxEvent:507937] STAT5 dimers translocate to the nucleus - v61:[modifyText] [_UpdateTracker:9789331] Update Tracker - [BlackBoxEvent:507937] STAT5 dimers translocate to the nucleus - v38:[modifyText] [_UpdateTracker:9789907] Update Tracker - [BlackBoxEvent:507937] STAT5 dimers translocate to the nucleus - v36:[modifyText]
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