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Details on Person Jupe, S, 2010-02-09
| Class:Id | InstanceEdit:507917 |
| _displayName | Jupe, S, 2010-02-09 |
| _timestamp | 2010-02-09 16:07:58 |
| author | [Person:391309] Jupe, Steve |
| dateTime | 2010-02-09 21:07:21 |
| (created) | [ModifiedResidue:507916] O4'-phospho-L-tyrosine at 384 [ModifiedResidue:507918] O4'-phospho-L-tyrosine at 387 [Complex:507919] p-STAT5 dimer [cytosol] [Homo sapiens] [ModifiedResidue:507920] O4'-phospho-L-tyrosine at 536 [Person:507921] Nelson, BH [Complex:507922] STAT5B homodimer [cytosol] [Homo sapiens] [Person:507923] Yoakim, M [Summation:507924] Shc is tyrosine phosphorylated by an unidentified kinase, cr... [ModifiedResidue:507925] O4'-phospho-L-tyrosine at 699 [LiteratureReference:507926] New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway |
| (modified) | [Pathway:451927] Interleukin-2 family signaling [Homo sapiens] [Reaction:451942] Within the IL-2R complex JAK3 phosphorylates JAK1 [Homo sapiens] [Reaction:452091] Phosphorylation of IL2RB Y338 enables SHC recruitment [Homo sapiens] [EntityWithAccessionedSequence:452093] p-Y364,Y418,Y536-IL2RB [plasma membrane] [Homo sapiens] [Complex:452095] IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:SHC [plasma membrane] [Homo sapiens] [Reaction:452097] Recruited STAT5 is phosphorylated [Homo sapiens] [Reaction:452099] DO NOT RELEASE - LCK phosphorylates multiple tyrosines of IL2RB [Homo sapiens] [Reaction:452100] SHC1 bound to IL2 receptor is phosphorylated [Homo sapiens] [Reaction:452102] p-STAT5 dimerizes [Homo sapiens] [Complex:452104] IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] [Homo sapiens] |
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No pathways have been reviewed or authored by Jupe, S, 2010-02-09 (507917)