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Details on Person Aquaporins passively transport water into cells

Class:Id	Reaction:507868
_displayName	Aquaporins passively transport water into cells
_doRelease	TRUE
_timestamp	2019-04-08 12:16:45
authored	[InstanceEdit:507886] May, B, 2010-02-09
catalystActivity	[CatalystActivity:507880] water channel activity of AQP0,1,2,3,4,5,7,8,9,10,11,12A [plasma membrane]
catalystActivityReference	[CatalystActivityReference:9644152] water channel activity of AQP0,1,2,3,4,5,7,8,9,10,11,12A [plasma membrane] Mechanism of selectivity in aquaporins and aquaglyceroporins
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:507878] May, B, 2010-02-09
edited	[InstanceEdit:507886] May, B, 2010-02-09
input	[SimpleEntity:109276] H2O [extracellular region]
isChimeric	FALSE
literatureReference	[LiteratureReference:503962] A refined structure of human aquaporin-1 [LiteratureReference:431685] Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein [LiteratureReference:503995] Aquaporin-1, nothing but a water channel [LiteratureReference:431788] Bidirectional water fluxes and specificity for small hydrophilic molecules in aquaporins 0-5 [LiteratureReference:431829] Cloning and functional expression of human aquaporin8 cDNA and analysis of its gene [LiteratureReference:431908] Functional and molecular characterization of the human neutral solute channel aquaporin-9 [LiteratureReference:504025] Functional characterization and localization of AQP3 in the human colon [LiteratureReference:503953] Functional characterization of a human aquaporin 0 mutation that leads to a congenital dominant lens cataract [LiteratureReference:431916] Functional characterization of human aquaporin 9 as a facilitative glycerol carrier [LiteratureReference:504017] Functional impairment of lens aquaporin in two families with dominantly inherited cataracts [LiteratureReference:504003] Identification of arylsulfonamides as Aquaporin 4 inhibitors [LiteratureReference:503955] Mechanism of selectivity in aquaporins and aquaglyceroporins [LiteratureReference:431959] Mercury-sensitive residues and pore site in AQP3 water channel [LiteratureReference:503948] Molecular cloning and characterization of an aquaporin cDNA from salivary, lacrimal, and respiratory tissues [LiteratureReference:503960] Molecular cloning and expression of a novel human aquaporin from adipose tissue with glycerol permeability [LiteratureReference:431970] Novel variants in human Aquaporin-4 reduce cellular water permeability [LiteratureReference:431978] Purification and functional characterization of aquaporin-8 [LiteratureReference:431981] Reconstitution of functional water channels in liposomes containing purified red cell CHIP28 protein [LiteratureReference:503930] Roles of aquaporin-3 water channels in volume-regulatory water flow in a human epithelial cell line [LiteratureReference:504004] Structural determinants of water permeation through aquaporin-1 [LiteratureReference:432234] The subcellular localization of an aquaporin-2 tetramer depends on the stoichiometry of phosphorylated and nonphosphorylated monomers [LiteratureReference:431832] Cloning and identification of a new member of water channel (AQP10) as an aquaglyceroporin [LiteratureReference:431837] Cloning of a new aquaporin (AQP10) abundantly expressed in duodenum and jejunum [LiteratureReference:504016] Human cataract lens membrane at subnanometer resolution [LiteratureReference:503921] Intact AQP0 performs cell-to-cell adhesion [LiteratureReference:503973] Aquaporin expression in normal human kidney and in renal disease [LiteratureReference:431795] CHIP28 water channels are localized in constitutively water-permeable segments of the nephron [LiteratureReference:431881] Distribution of aquaporin water channels AQP1 and AQP5 in the ductal system of the human pancreas [LiteratureReference:503972] Expression of the AQP-1 water channel in normal human tissues: a semiquantitative study using tissue microarray technology [LiteratureReference:431931] Identification, purification, and partial characterization of a novel Mr 28,000 integral membrane protein from erythrocytes and renal tubules [LiteratureReference:503997] Cloning, characterization, and chromosomal mapping of human aquaporin of collecting duct [LiteratureReference:431878] Distribution of AQP2 and AQP3 water channels in human tissue microarrays [LiteratureReference:431999] Requirement of human renal water channel aquaporin-2 for vasopressin-dependent concentration of urine [LiteratureReference:481053] Role of multiple phosphorylation sites in the COOH-terminal tail of aquaporin-2 for water transport: evidence against channel gating [LiteratureReference:504022] Water channel expression in human ADPKD kidneys [LiteratureReference:431853] Compartmentalization of aquaporins in the human intestine [LiteratureReference:503934] Crystal structure of human aquaporin 4 at 1.8 A and its mechanism of conductance [LiteratureReference:431887] Distribution of the AQP4 water channel in normal human tissues: protein and tissue microarrays reveal expression in several new anatomical locations, including the prostate gland and seminal vesicles [LiteratureReference:503990] The human AQP4 gene: definition of the locus encoding two water channel polypeptides in brain [LiteratureReference:431922] High-resolution x-ray structure of human aquaporin 5 [LiteratureReference:432006] The human Aquaporin-5 gene. Molecular characterization and chromosomal localization [LiteratureReference:431848] Comparison of messenger RNA distribution for 60 proteins in fat cells vs the nonfat cells of human omental adipose tissue [LiteratureReference:431860] Differential expression of aquaporin 7 in adipose tissue of lean and obese high fat consumers [LiteratureReference:503956] Human aquaporin adipose (AQPap) gene. Genomic structure, promoter analysis and functional mutation [LiteratureReference:431869] Differential expression of aquaporin 8 in human colonic epithelial cells and colorectal tumors [LiteratureReference:431903] Expression of aquaporin 8 in colonic epithelium with diarrhoea-predominant irritable bowel syndrome [LiteratureReference:504036] Knockdown of hepatocyte aquaporin-8 by RNA interference induces defective bile canalicular water transport [LiteratureReference:431678] Altered aquaporin 9 expression and localization in human hepatocellular carcinoma [LiteratureReference:431939] Immunolocalization of AQP9 in liver, epididymis, testis, spleen, and brain [LiteratureReference:879877] Point mutations in the aromatic/arginine region in aquaporin 1 allow passage of urea, glycerol, ammonia, and protons [LiteratureReference:879852] Concerted action of two cation filters in the aquaporin water channel [LiteratureReference:913485] Electrostatics of aquaporin and aquaglyceroporin channels correlates with their transport selectivity [LiteratureReference:2754726] Water permeability and characterization of aquaporin-11 [LiteratureReference:8862060] In silico study of human aquaporin AQP11 and AQP12 channels
modified	[InstanceEdit:507888] May, B, 2010-02-09 [InstanceEdit:771692] May, B, 2010-05-21 [InstanceEdit:847706] May, B, 2010-05-30 [InstanceEdit:879864] May, B, 2010-06-24 [InstanceEdit:913480] May, B, 2010-07-15 [InstanceEdit:918084] May, B, 2010-07-31 [InstanceEdit:927718] May, B, 2010-08-06 [InstanceEdit:939819] May, B, 2010-09-01 [InstanceEdit:947457] May, B, 2010-09-06 [InstanceEdit:1973932] D'Eustachio, P, 2011-11-06 [InstanceEdit:2754729] May, B, 2012-12-10 [InstanceEdit:5251387] May, B, 2014-02-03 [InstanceEdit:8862067] Jupe, Steve, 2016-02-25 [InstanceEdit:8865030] D'Eustachio, Peter, 2016-03-18 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9644154] May, Bruce, 2019-04-08 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Aquaporins passively transport water into cells
output	[SimpleEntity:29356] H2O [cytosol]
releaseDate	2009-06-24
reverseReaction	[Reaction:507870] Aquaporins passively transport water out of cells [Homo sapiens] [Reaction:507868] Aquaporins passively transport water into cells [Homo sapiens]
reviewed	[InstanceEdit:879857] Beitz, E, 2010-06-24 [InstanceEdit:913479] Calamita, G, 2010-07-15 [InstanceEdit:918100] Mathai, JC, MacIver, B, 2010-07-31
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105895] R-HSA-507868.5
summation	[Summation:507876] Aquaporin-0 (AQP0, also known as MIP), AQP1, AQP2, AQP3, AQP...
(hasEvent)	[Pathway:432047] Passive transport by Aquaporins [Homo sapiens]
(reverseReaction)	[Reaction:507870] Aquaporins passively transport water out of cells [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9783340] Update Tracker - [Reaction:507868] Aquaporins passively transport water into cells - v57:[addLiteratureReference, modifyText] [_UpdateTracker:9787936] Update Tracker - [Reaction:507868] Aquaporins passively transport water into cells - v44:[addLiteratureReference, modifyText]
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No pathways have been reviewed or authored by Aquaporins passively transport water into cells (507868)