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Details on Person UniProt:O96024 B3GALT4
Class:Id
ReferenceGeneProduct:50613
_chainChangeLog
chain:1-378 added on Fri February 6 2015
_displayName
UniProt:O96024 B3GALT4
_timestamp
2025-02-21 18:54:33
chain
chain:1-378
checksum
4E55DFC72AE96213
comment
FUNCTION Involved in GM1/GD1B/GA1 ganglioside biosynthesis.CATALYTIC ACTIVITY a ganglioside GM2 (d18:1(4E)) + UDP-alpha-D-galactose = a ganglioside GM1 (d18:1(4E)) + UDP + H(+)CATALYTIC ACTIVITY a ganglioside GM2 + UDP-alpha-D-galactose = a ganglioside GM1 + UDP + H(+)CATALYTIC ACTIVITY a ganglioside GD2 (d18:1(4E)) + UDP-alpha-D-galactose = a ganglioside GD1b (d18:1(4E)) + UDP + H(+)CATALYTIC ACTIVITY a ganglioside GA2 (d18:1(4E)) + UDP-alpha-D-galactose = a ganglioside GA1 (d18:1(4E)) + UDP + H(+)PATHWAY Protein modification; protein glycosylation.SUBCELLULAR LOCATION Highly expressed in heart, skeletal muscle and pancreas and, to a lesser extent, in brain, placenta, kidney, liver and lung.SIMILARITY Belongs to the glycosyltransferase 31 family.ONLINE INFORMATION Beta-1,3-galactosyltransferase 4
