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Details on Person Cytosolic CTP synthase 2 (CTPS) catalyzes the reaction of UT...

Class:IdSummation:504060
_displayNameCytosolic CTP synthase 2 (CTPS) catalyzes the reaction of UT...
_timestamp2010-02-05 22:22:49
created[InstanceEdit:504056] D'Eustachio, P, 2010-02-05
modified[InstanceEdit:504062] D'Eustachio, P, 2010-02-05
textCytosolic CTP synthase 2 (CTPS) catalyzes the reaction of UTP, glutamine, ATP and water to form CTP, glutamate, ADP, and orthophosphate (Han et al. 2005; van Kuilenberg et al. 2000). Unpublished X-ray crystallographic data suggest that the enzyme is a tetramer (PDB 3IHL). Both CTPS2 and a second human gene product, CPTS, have CTP synthase activity in various test systems; their relative contributions to CTP metabolism in the body is not clear.
(summation)[Reaction:504054] Amination of uridine 5'-triphosphate (UTP) to form cytidine 5'-triphosphate (CTPS2) [Homo sapiens]
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