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Details on Person UniProt:P05090 APOD
| Class:Id | ReferenceGeneProduct:50158 |
|---|---|
| _chainChangeLog | signal peptide:1-20 added on Fri February 6 2015;chain:21-189 added on Fri February 6 2015 |
| _displayName | UniProt:P05090 APOD |
| _timestamp | 2025-02-21 19:56:32 |
| chain | signal peptide:1-20 chain:21-189 |
| checksum | 0EAA6DE03D5E71A8 |
| comment | FUNCTION APOD occurs in the macromolecular complex with lecithin-cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts.SUBUNIT Homodimer. In plasma, also exists as a disulfide-linked heterodimer with APOA2.INTERACTION Expressed in liver, intestine, pancreas, kidney, placenta, adrenal, spleen, fetal brain tissue and tears.PTM N-glycosylated. N-glycan heterogeneity at Asn-65: Hex5HexNAc4 (major) and Hex6HexNAc5 (minor); at Asn-98: Hex5HexNAc4 (minor), dHex1Hex5HexNAc4 (major), dHex1Hex6HexNAc5 (minor) and dHex1Hex7HexNAc6 (minor).MISCELLANEOUS APOD is primarily localized in HDL (60-65%), with most of the remainder in VHDL and only trace amounts in VLDL and LDL.SIMILARITY Belongs to the calycin superfamily. Lipocalin family. |
| description | recommendedName: Apolipoprotein D shortName: Apo-D shortName: ApoD |
| geneName | APOD |
| identifier | P05090 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Direct protein sequencing Disulfide bond Glycoprotein Lipid-binding Proteomics identification Pyrrolidone carboxylic acid Reference proteome Secreted Signal Transport |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9939033] Weiser, Joel, 2025-02-21 |
| name | APOD |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8996421] ENSEMBL:ENSG00000189058 APOD [Homo sapiens] |
| secondaryIdentifier | APOD_HUMAN B2R579 D3DNW6 Q6IBG6 |
| sequenceLength | 189 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:5216199] APOD [extracellular region] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P05090 APOD (50158)
