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Details on Person POU5F1 (OCT4), SOX2, and NANOG bind distinct sites in the pr...
| Class:Id | Summation:500369 |
|---|---|
| _displayName | POU5F1 (OCT4), SOX2, and NANOG bind distinct sites in the pr... |
| _timestamp | 2014-01-23 02:07:40 |
| created | [InstanceEdit:500370] May, B, 2010-02-03 |
| modified | [InstanceEdit:500403] May, B, 2010-02-03 [InstanceEdit:1014235] May, B, 2010-11-13 [InstanceEdit:1101836] May, B, 2010-12-01 [InstanceEdit:2888916] May, B, 2012-12-31 [InstanceEdit:2975872] May, B, 2013-01-09 [InstanceEdit:3656308] May, B, 2013-06-03 [InstanceEdit:5159238] D'Eustachio, P, 2013-11-22 [InstanceEdit:5246733] May, B, 2014-01-23 |
| text | POU5F1 (OCT4), SOX2, and NANOG bind distinct sites in the promoter of the POU5F1 gene (Boyer et al. 2005, Chew et al. 2005, Rodda et al. 2005, Jin et al. 2007, Lister et al. 2009, Jung et al. 2010, Goke et al. 2011). The set of target genes of POU5F1, SOX2, and NANOG includes POU5F1, SOX2, and NANOG themselves, thus their expression is a component of an autoregulatory loop . Activin/Nodal signaling also regulates POU5F1 transcription via SMAD2 and SMAD3 (Brown et al. 2011). PRDM14 binds the POU5F1 promoter and regulates transcription (Chia et al. 2010). |
| (summation) | [Reaction:1112609] POU5F1 (OCT4), SOX2, NANOG, ZSCAN10, PRDM14, SMAD2, FOXP1-ES bind the POU5F1 (OCT4) promoter [Homo sapiens] |
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No pathways have been reviewed or authored by POU5F1 (OCT4), SOX2, and NANOG bind distinct sites in the pr... (500369)
