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Details on Person D'Eustachio, P, 2010-01-31
| Class:Id | InstanceEdit:500141 |
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| _displayName | D'Eustachio, P, 2010-01-31 |
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| _timestamp | 2010-01-31 23:22:03 |
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| author | [Person:140934] D'Eustachio, Peter |
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| dateTime | 2010-02-01 04:21:44 |
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| (created) | [LiteratureReference:500137] Alteration of enzyme specificity by computational loop remodeling and design
[Person:500138] Murphy, PM
[Person:500139] Bolduc, JM
[Person:500140] Yamaguchi, Y
[Person:500142] Matsumura, T
[Person:500143] Stoddard, Barry L
[Person:500144] Baker, D
[Person:500145] Gallaher, JL
[Person:500146] Ichida, K
[LiteratureReference:500147] Human xanthine oxidase changes its substrate specificity to aldehyde oxidase type upon mutation of amino acid residues in the active site: roles of active site residues in binding and activation of purine substrate |
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| (modified) | [Complex:74244] XDH dimer [cytosol] [Homo sapiens]
[CatalystActivity:74246] xanthine oxidase activity of XDH dimer [cytosol]
[Reaction:74247] XDH oxidizes hypoxanthine to form xanthine [Homo sapiens]
[Complex:74253] GDA dimer [cytosol] [Homo sapiens]
[CatalystActivity:74254] guanine deaminase activity of GDA dimer [cytosol]
[Reaction:74255] Guanine + H2O => Xanthine + NH4+ [Homo sapiens]
[Reaction:74258] XDH oxidizes xanthine to form urate [Homo sapiens]
[Summation:178834] Cytosolic guanine deaminase (GDA) catalyzes the reaction of ...
[Summation:178880] Cytosolic xanthine dehydrogenase (XDH) in its oxidase form c...
[Summation:179337] Cytosolic xanthine dehydrogenase (XDH) in its oxidase form c... |
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No pathways have been reviewed or authored by D'Eustachio, P, 2010-01-31 (500141)
