Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person UniProt:O00170 AIP
| Class:Id | ReferenceGeneProduct:49818 |
|---|---|
| _chainChangeLog | chain:1-330 added on Fri February 6 2015 |
| _displayName | UniProt:O00170 AIP |
| _timestamp | 2025-08-15 21:28:12 |
| chain | chain:1-330 |
| checksum | C331AA6D0F8D8F53 |
| comment | FUNCTION May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting.FUNCTION Cellular negative regulator of the hepatitis B virus (HBV) X protein.SUBUNIT Interacts with RET in the pituitary gland; this interaction prevents the formation of the AIP-survivin complex.INTERACTION Widely expressed. Higher levels seen in the heart, placenta and skeletal muscle. Not expressed in the liver.DISEASE The disease is caused by variants affecting the gene represented in this entry. |
| description | recommendedName: AH receptor-interacting protein shortName: AIP alternativeName: Aryl-hydrocarbon receptor-interacting protein alternativeName: HBV X-associated protein 2 shortName: XAP-2 alternativeName: Immunophilin homolog ARA9 |
| geneName | AIP XAP2 |
| identifier | O00170 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Cushing syndrome Cytoplasm Phosphoprotein Proteomics identification Reference proteome Repeat TPR repeat |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9963647] Weiser, Joel, 2025-08-15 |
| name | AIP |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8950530] ENSEMBL:ENSG00000110711 AIP [Homo sapiens] |
| secondaryIdentifier | AIP_HUMAN A0SZW3 A0SZW4 A0SZW5 A0SZW6 G9I2H4 Q2M3Q2 Q99606 |
| sequenceLength | 330 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:8936839] AIP [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:8937156] AIP [nucleoplasm] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:O00170 AIP (49818)
