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Details on Person UniProt:P35611 ADD1
Class:Id
ReferenceGeneProduct:49704
_chainChangeLog
chain:1-737 added on Sat February 7 2015
_displayName
UniProt:P35611 ADD1
_timestamp
2024-11-03 20:13:07
chain
chain:1-737
checksum
DF13AB30B12F20B6
comment
FUNCTION Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin.SUBUNIT Heterodimer of an alpha and a beta subunit or an alpha and a gamma subunit.INTERACTION Additional isoforms seem to exist.TISSUE SPECIFICITY Expressed in all tissues. Found in much higher levels in reticulocytes than the beta subunit.DOMAIN Each subunit is comprised of three regions: a NH2-terminal protease-resistant globular head region, a short connecting subdomain, and a protease-sensitive tail region.SIMILARITY Belongs to the aldolase class II family. Adducin subfamily.
