Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person UniProt:Q9Y3Q7 ADAM18

Class:Id	ReferenceGeneProduct:49680
_chainChangeLog	signal peptide:1-16 added on Fri February 6 2015;propeptide:17-184 added on Fri February 6 2015;chain:185-739 added on Fri February 6 2015
_displayName	UniProt:Q9Y3Q7 ADAM18
_timestamp	2024-08-09 18:58:45
chain	signal peptide:1-16 propeptide:17-184 chain:185-739
checksum	2D8BE9A975072CDD
comment	FUNCTION Sperm surface membrane protein that may be involved in spermatogenesis and fertilization. This is a non catalytic metalloprotease-like protein (By similarity).SUBCELLULAR LOCATION Expressed specifically in testis.DOMAIN A tripeptide motif (ECD) within disintegrin-like domain could be involved in the binding to egg integrin receptor and thus could mediate sperm/egg binding.PTM The prodomain and the metalloprotease-like domain are cleaved during the epididymal maturation of the spermatozoa.
description	recommendedName: Disintegrin and metalloproteinase domain-containing protein 18 shortName: ADAM 18 alternativeName: Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III shortName: tMDC III
geneName	ADAM18 TMDC3 UNQ858/PRO1867
identifier	Q9Y3Q7
isSequenceChanged	FALSE
keyword	Alternative splicing Developmental protein Differentiation Disulfide bond EGF-like domain Glycoprotein Membrane Proteomics identification Reference proteome Signal Spermatogenesis Transmembrane Transmembrane helix
modified	[InstanceEdit:84067] Schmidt, EE, 2003-12-18 04:29:09 [InstanceEdit:143527] Schmidt, EE, 2004-11-12 07:45:10 [InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53 [InstanceEdit:354386] Schmidt, EE, 2008-06-18 04:45:12 [InstanceEdit:384350] Kanapin, AA, 2008-11-26 14:00:39 [InstanceEdit:392885] Kanapin, AA, 2009-03-09 12:07:18 [InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35 [InstanceEdit:423310] Kanapin, AA [InstanceEdit:435478] Kanapin, AA [InstanceEdit:435871] Kanapin, AA [InstanceEdit:447347] Kanapin, AA [InstanceEdit:525883] Kanapin, AA [InstanceEdit:613449] Kanapin, AA [InstanceEdit:797602] Kanapin, AA [InstanceEdit:937368] Yung, CK [InstanceEdit:1042053] Yung, CK [InstanceEdit:1220657] Yung, CK [InstanceEdit:1300696] Yung, CK [InstanceEdit:1301627] Yung, CK [InstanceEdit:1551960] Weiser, JD [InstanceEdit:1995863] Weiser, JD [InstanceEdit:2132304] Weiser, JD [InstanceEdit:2265580] Weiser, JD [InstanceEdit:5433710] Weiser, JD [InstanceEdit:5618415] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:8987656] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9657908] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9715482] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9917590] Weiser, Joel, 2024-08-09
name	ADAM18
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:9001585] ENSEMBL:ENSG00000168619 ADAM18 [Homo sapiens]
secondaryIdentifier	ADA18_HUMAN B2R9Y0 Q0VAI4 Q6IRW9 Q6UXJ9
sequenceLength	739
species	[Species:48887] Homo sapiens
(isoformParent)	[ReferenceIsoform:217980] UniProt:Q9Y3Q7-2 ADAM18 [Homo sapiens] [ReferenceIsoform:415996] UniProt:Q9Y3Q7-1 ADAM18 [Homo sapiens] [ReferenceIsoform:8969934] UniProt:Q9Y3Q7-3 ADAM18 [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by UniProt:Q9Y3Q7 ADAM18 (49680)