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Details on Person UniProt:P61164 Actr1a
Class:Id
ReferenceGeneProduct:49645
_chainChangeLog
chain:1-376 added on Sat February 7 2015
_displayName
UniProt:P61164 Actr1a
_timestamp
2023-11-03 16:18:03
chain
chain:1-376
checksum
4A978E7AB3739436
comment
FUNCTION Part of the ACTR1A/ACTB filament around which the dynactin complex is built. The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules.SUBUNIT Part of the ACTR1A/ACTB filament around which the dynactin complex is built. The filament contains 8 copies of ACTR1A and 1 ACTB. Interacts with dynein and adapters such as BICD2 (By similarity). Interacts with BCCIP (isoform 2/alpha) (By similarity).SUBCELLULAR LOCATION Belongs to the actin family. ARP1 subfamily.
