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Details on Person UniProt:P08173 CHRM4
| Class:Id | ReferenceGeneProduct:49546 |
|---|---|
| _chainChangeLog | chain:1-479 added on Fri February 6 2015 |
| _displayName | UniProt:P08173 CHRM4 |
| _timestamp | 2024-11-03 20:13:05 |
| chain | chain:1-479 |
| checksum | 9C1B05B359A64289 |
| comment | FUNCTION The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase.SUBCELLULAR LOCATION Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM4 sub-subfamily. |
| description | recommendedName: Muscarinic acetylcholine receptor M4 |
| geneName | CHRM4 |
| identifier | P08173 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Postsynaptic cell membrane Proteomics identification Receptor Reference proteome Synapse Transducer Transmembrane Transmembrane helix |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | CHRM4 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:9002183] ENSEMBL:ENSG00000180720 CHRM4 [Homo sapiens] |
| secondaryIdentifier | ACM4_HUMAN B2RPP4 Q0VD60 Q4VBK7 |
| sequenceLength | 479 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:390693] CHRM4 [plasma membrane] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P08173 CHRM4 (49546)
