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Details on Person UniProt:P61967 Ap1s1
| Class:Id | ReferenceGeneProduct:49256 |
|---|---|
| _chainChangeLog | chain:1-158 added on Sat February 7 2015 |
| _displayName | UniProt:P61967 Ap1s1 |
| _timestamp | 2023-11-03 15:14:28 |
| chain | chain:1-158 |
| checksum | E461937790406D8B |
| comment | FUNCTION Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.SUBUNIT Adaptor protein complex 1 (AP-1) is a heterotetramer composed of two large adaptins (gamma-type subunit AP1G1 and beta-type subunit AP1B1), a medium adaptin (mu-type subunit AP1M1 or AP1M2) and a small adaptin (sigma-type subunit AP1S1 or AP1S2 or AP1S3).SUBCELLULAR LOCATION Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.TISSUE SPECIFICITY Detected in brain and embryonic stem cells.SIMILARITY Belongs to the adaptor complexes small subunit family. |
| description | recommendedName: AP-1 complex subunit sigma-1A alternativeName: Adaptor protein complex AP-1 subunit sigma-1A alternativeName: Adaptor-related protein complex 1 subunit sigma-1A alternativeName: Clathrin assembly protein complex 1 sigma-1A small chain alternativeName: Clathrin coat assembly protein AP19 alternativeName: Golgi adaptor HA1/AP1 adaptin sigma-1A subunit alternativeName: HA1 19 kDa subunit alternativeName: Sigma 1a subunit of AP-1 clathrin alternativeName: Sigma-adaptin 1A alternativeName: Sigma1A-adaptin |
| geneName | Ap1s1 Ap19 |
| identifier | P61967 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Coated pit Cytoplasmic vesicle Golgi apparatus Membrane Phosphoprotein Protein transport Reference proteome Transport |
| modified | [InstanceEdit:84067] Schmidt, EE, 2003-12-18 04:29:09 [InstanceEdit:143527] Schmidt, EE, 2004-11-12 07:45:10 [InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53 [InstanceEdit:354386] Schmidt, EE, 2008-06-18 04:45:12 [InstanceEdit:384350] Kanapin, AA, 2008-11-26 14:00:39 [InstanceEdit:392885] Kanapin, AA, 2009-03-09 12:07:18 [InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35 [InstanceEdit:423310] Kanapin, AA [InstanceEdit:435478] Kanapin, AA [InstanceEdit:435871] Kanapin, AA [InstanceEdit:447347] Kanapin, AA [InstanceEdit:525883] Kanapin, AA [InstanceEdit:613449] Kanapin, AA [InstanceEdit:797602] Kanapin, AA [InstanceEdit:937368] Yung, CK [InstanceEdit:1042053] Yung, CK [InstanceEdit:1220657] Yung, CK [InstanceEdit:1300696] Yung, CK [InstanceEdit:1301627] Yung, CK [InstanceEdit:1551960] Weiser, JD [InstanceEdit:1995863] Weiser, JD [InstanceEdit:2132304] Weiser, JD [InstanceEdit:2265580] Weiser, JD [InstanceEdit:2587579] Weiser, JD [InstanceEdit:5083144] Weiser, JD [InstanceEdit:5263031] Weiser, JD [InstanceEdit:5433710] Weiser, JD [InstanceEdit:5618415] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 |
| name | Ap1s1 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | AP1S1_MOUSE P82267 Q00382 Q9BTN4 Q9UDW9 |
| sequenceLength | 158 |
| species | [Species:48892] Mus musculus |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P61967 Ap1s1 (49256)
