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Details on Person pS37,T41,S45-CTNNB1 S33F [cytosol]

Class:Id	EntityWithAccessionedSequence:4839628
_displayName	pS37,T41,S45-CTNNB1 S33F [cytosol]
_timestamp	2014-11-20 03:56:25
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:4839629] Rothfels, K, 2013-11-01
crossReference	[DatabaseIdentifier:4839572] COSMIC:COSV62688300
disease	[Disease:1500689] cancer [Disease:4839607] central nervous system cancer [Disease:2327993] hepatocellular carcinoma [Disease:2328001] skin squamous cell carcinoma [Disease:2317358] endometrial cancer
endCoordinate	781
hasModifiedResidue	[ModifiedResidue:4839603] O-phospho-L-serine at 45 [ModifiedResidue:4839605] O-phospho-L-threonine at 41 [ModifiedResidue:4839602] O-phospho-L-serine at 37 [ReplacedResidue:4839587] L-serine 33 replaced with L-phenylalanine
literatureReference	[LiteratureReference:5255496] Illegitimate WNT pathway activation by beta-catenin mutation or autocrine stimulation in T-cell malignancies [LiteratureReference:5251485] Genetic alterations associated with hepatocellular carcinomas define distinct pathways of hepatocarcinogenesis [LiteratureReference:5251510] Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas
modified	[InstanceEdit:5255514] Rothfels, K, 2014-02-06
name	pS37,T41,S45-CTNNB1 S33F pS37,T41,S45-beta catenin S33F
referenceEntity	[ReferenceGeneProduct:403799] UniProt:P35222 CTNNB1 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5647745] R-HSA-4839628.1
startCoordinate	1
(hasCandidate)	[CandidateSet:4839627] pS37,T41,S45-CTNNB1 S33 mutants [cytosol] [Homo sapiens]
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No pathways have been reviewed or authored by pS37,T41,S45-CTNNB1 S33F [cytosol] (4839628)