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Details on Person pS45-CTNNB1 T41I [cytosol]

Class:Id	EntityWithAccessionedSequence:4839612
_displayName	pS45-CTNNB1 T41I [cytosol]
_timestamp	2014-11-20 03:04:35
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:4839611] Rothfels, K, 2013-11-01
crossReference	[DatabaseIdentifier:4839578] COSMIC:COSV62688008
disease	[Disease:1500689] cancer [Disease:2317358] endometrial cancer [Disease:2327993] hepatocellular carcinoma [Disease:2327990] pituitary cancer
endCoordinate	781
hasModifiedResidue	[ReplacedResidue:4839599] L-threonine 41 replaced with L-isoleucine [ModifiedResidue:4839603] O-phospho-L-serine at 45
literatureReference	[LiteratureReference:5251469] AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1 [LiteratureReference:5251472] Abnormalities of the APC/beta-catenin pathway in endometrial cancer [LiteratureReference:5251510] Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas
modified	[InstanceEdit:5251686] Rothfels, K, 2014-02-04 [InstanceEdit:5255511] Rothfels, K, 2014-02-06
name	pS45-CTNNB1 T41I Catenin beta-1 CTNB1_HUMAN
referenceEntity	[ReferenceGeneProduct:403799] UniProt:P35222 CTNNB1 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5645482] R-HSA-4839612.1
startCoordinate	1
(hasCandidate)	[CandidateSet:4839614] pS45-CTNNB1 T41 mutants [cytosol] [Homo sapiens]
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No pathways have been reviewed or authored by pS45-CTNNB1 T41I [cytosol] (4839612)