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Details on Person pS45-CTNNB1 T41A [cytosol]

Class:Id	EntityWithAccessionedSequence:4836868
_displayName	pS45-CTNNB1 T41A [cytosol]
_timestamp	2014-11-20 03:08:10
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:4836870] Rothfels, K, 2013-10-30
crossReference	[DatabaseIdentifier:4836866] COSMIC:COSV62687862 [DatabaseIdentifier:4836869] COSMIC:COSM13153
disease	[Disease:1500689] cancer [Disease:2317358] endometrial cancer [Disease:2327993] hepatocellular carcinoma [Disease:4791250] colorectal cancer [Disease:4791269] adrenal gland cancer [Disease:4839609] connective tissue cancer
endCoordinate	781
hasModifiedResidue	[ReplacedResidue:4836867] L-threonine 41 replaced with L-alanine [ModifiedResidue:4839603] O-phospho-L-serine at 45
literatureReference	[LiteratureReference:5251469] AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1 [LiteratureReference:5246621] Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
modified	[InstanceEdit:4839649] Rothfels, K, 2013-11-01 [InstanceEdit:5251685] Rothfels, K, 2014-02-04
name	pS45-CTNNB1 T41A Catenin beta-1 CTNB1_HUMAN
referenceEntity	[ReferenceGeneProduct:403799] UniProt:P35222 CTNNB1 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5645639] R-HSA-4836868.1
startCoordinate	1
(hasCandidate)	[CandidateSet:4839614] pS45-CTNNB1 T41 mutants [cytosol] [Homo sapiens]
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No pathways have been reviewed or authored by pS45-CTNNB1 T41A [cytosol] (4836868)