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Details on Person POU5F1 (OCT4), SOX2, NANOG bind the SOX2 promoter
Class:Id Reaction:480685 _displayName POU5F1 (OCT4), SOX2, NANOG bind the SOX2 promoter _doRelease TRUE _timestamp 2014-11-20 02:41:13 authored [InstanceEdit:1013049] May, B, 2010-11-12 compartment [Compartment:7660] nucleoplasm created [InstanceEdit:480249] May, B, 2010-01-27 edited [InstanceEdit:1013049] May, B, 2010-11-12 input [EntityWithAccessionedSequence:452586] NANOG [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:452472] POU5F1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:452271] SOX2 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:2888991] SOX2 gene [nucleoplasm] [Homo sapiens] isChimeric FALSE literatureReference [LiteratureReference:452538] Core transcriptional regulatory circuitry in human embryonic stem cells [LiteratureReference:452197] Reciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cells [LiteratureReference:452445] Transcriptional regulation of nanog by OCT4 and SOX2 [LiteratureReference:452628] Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells [LiteratureReference:2972938] Combinatorial binding in human and mouse embryonic stem cells identifies conserved enhancers active in early embryonic development [LiteratureReference:1112612] A data integration approach to mapping OCT4 gene regulatory networks operative in embryonic stem cells and embryonal carcinoma cells [LiteratureReference:5246719] Human DNA methylomes at base resolution show widespread epigenomic differences [LiteratureReference:5246714] Identification of an OCT4 and SRY regulatory module using integrated computational and experimental genomics approaches modified [InstanceEdit:480941] May, B, 2010-01-27 [InstanceEdit:500370] May, B, 2010-02-03 [InstanceEdit:1013055] May, B, 2010-11-12 [InstanceEdit:1086967] May, B, 2010-11-29 [InstanceEdit:2889038] May, B, 2012-12-31 [InstanceEdit:2895780] May, B, 2013-01-03 [InstanceEdit:2972981] D'Eustachio, P, 2013-01-06 [InstanceEdit:2975872] May, B, 2013-01-09 [InstanceEdit:3108239] May, B, 2013-02-10 [InstanceEdit:3165216] May, B, 2013-02-22 [InstanceEdit:4411347] May, B, 2013-08-23 [InstanceEdit:4420242] May, B, 2013-08-31 [InstanceEdit:5159238] D'Eustachio, P, 2013-11-22 [InstanceEdit:5246709] May, B, 2014-01-22 [InstanceEdit:5246733] May, B, 2014-01-23 [InstanceEdit:5251384] May, B, 2014-02-03 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 name POU5F1 (OCT4), SOX2, NANOG bind the SOX2 promoter output [Complex:480572] POU5F1:SOX2:NANOG:SOX2 gene [nucleoplasm] [Homo sapiens] precedingEvent
releaseDate 2014-03-12 reviewed [InstanceEdit:5246708] Wang, Jianlong, 2014-01-22 reviewStatus [ReviewStatus:9821382] five stars species [Species:48887] Homo sapiens stableIdentifier [StableIdentifier:5644576] R-HSA-480685.2 summation [Summation:2888917] POU5F1 (OCT4), SOX2, and NANOG bind distinct sites in the pr... (hasEvent) [Pathway:452723] Transcriptional regulation of pluripotent stem cells [Homo sapiens] (precedingEvent) [BlackBoxEvent:452701] Expression of DPPA4 [Homo sapiens] [BlackBoxEvent:452883] Expression of Histone H4 (HIST1H4E) [Homo sapiens] [BlackBoxEvent:452894] Expression of SOX2 [Homo sapiens] [BlackBoxEvent:453072] Expression of USP44 [Homo sapiens] [BlackBoxEvent:453073] Expression of peroxisomal sarcosine oxidase (PIPOX) [Homo sapiens] [BlackBoxEvent:480238] Expression of FOXO1A [Homo sapiens] [BlackBoxEvent:480338] Expression of LINGO1 (LRRN6A) [Homo sapiens] [BlackBoxEvent:480435] Expression of SET [Homo sapiens] [BlackBoxEvent:480443] Expression of NFE2L3 (NRF3) [Homo sapiens] [BlackBoxEvent:480539] Expression of Histone Acetyltransferase MYST3/MOZ [Homo sapiens]
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