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Details on Person Expression of Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (PIP5K1C)

Class:Id	BlackBoxEvent:480484
_displayName	Expression of Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (PIP5K1C)
_doRelease	FALSE
_timestamp	2018-10-31 14:30:10
authored	[InstanceEdit:1013049] May, B, 2010-11-12
compartment	[Compartment:7660] nucleoplasm [Compartment:70101] cytosol
created	[InstanceEdit:480249] May, B, 2010-01-27
edited	[InstanceEdit:1013049] May, B, 2010-11-12
input	[EntityWithAccessionedSequence:2888968] PIP5K1C gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:480446] Lethal contractural syndrome type 3 (LCCS3) is caused by a mutation in PIP5K1C, which encodes PIPKI gamma of the phophatidylinsitol pathway [LiteratureReference:452628] Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells [LiteratureReference:480180] Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin [LiteratureReference:480653] Type I gamma phosphatidylinositol phosphate kinase modulates invasion and proliferation and its expression correlates with poor prognosis in breast cancer [LiteratureReference:480262] PI5KI-dependent signals are critical regulators of the cytolytic secretory pathway [LiteratureReference:480177] Type I gamma phosphatidylinositol phosphate kinase is required for EGF-stimulated directional cell migration [LiteratureReference:452538] Core transcriptional regulatory circuitry in human embryonic stem cells [LiteratureReference:452948] In silico identification of a core regulatory network of OCT4 in human embryonic stem cells using an integrated approach [LiteratureReference:1101864] Deciphering the lithium transcriptome: microarray profiling of lithium-modulated gene expression in human neuronal cells [LiteratureReference:1101866] Changes in transcription profile and cytoskeleton morphology in pelvic ligament fibroblasts in response to stretch: the effects of estradiol and levormeloxifene
modified	[InstanceEdit:480941] May, B, 2010-01-27 [InstanceEdit:1013055] May, B, 2010-11-12 [InstanceEdit:1086967] May, B, 2010-11-29 [InstanceEdit:1101836] May, B, 2010-12-01 [InstanceEdit:2892244] May, B, 2012-12-31 [InstanceEdit:3108239] May, B, 2013-02-10 [InstanceEdit:3165216] May, B, 2013-02-22 [InstanceEdit:4411347] May, B, 2013-08-23 [InstanceEdit:4420242] May, B, 2013-08-31 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9627000] May, Bruce, 2018-10-31 [InstanceEdit:9641190] Wu, G, 2019-04-04
name	Expression of Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (PIP5K1C)
output	[EntityWithAccessionedSequence:392427] PIP5K1C [cytosol] [Homo sapiens]
regulatedBy	[NegativeGeneExpressionRegulation:5163251] Negative gene expression regulation by 'POU5F1:SOX2:PIP5K1C gene [nucleoplasm]'
regulationReference	[RegulationReference:9642300] Negative gene expression regulation by 'POU5F1:SOX2:PIP5K1C gene [nucleoplasm]' Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8927654] R-HSA-480484.1
summation	[Summation:480611] The PIP5K1C gene is transcribed to yield mRNA and the mRNA i...
(hasEvent)	[Pathway:500407] Individual Binding Reactions and Reactions Regulated by Pluripotency Factors [Homo sapiens]
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No pathways have been reviewed or authored by Expression of Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (PIP5K1C) (480484)