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Details on Person POU5F1:SOX2:NANOG:KLF4:PBX1:SMAD2:FOXP1-ES:NANOG gene [nucleoplasm]

Class:IdComplex:480463
_displayNamePOU5F1:SOX2:NANOG:KLF4:PBX1:SMAD2:FOXP1-ES:NANOG gene [nucleoplasm]
_timestamp2016-09-18 08:55:32
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:480249] May, B, 2010-01-27
hasComponent
isChimericFALSE
literatureReference[LiteratureReference:480780] KLF4 and PBX1 directly regulate NANOG expression in human embryonic stem cells
[LiteratureReference:2888922] Activin/Nodal signaling controls divergent transcriptional networks in human embryonic stem cells and in endoderm progenitors
[LiteratureReference:452538] Core transcriptional regulatory circuitry in human embryonic stem cells
[LiteratureReference:452445] Transcriptional regulation of nanog by OCT4 and SOX2
[LiteratureReference:2888933] OCT4/SOX2-independent Nanog autorepression modulates heterogeneous Nanog gene expression in mouse ES cells
[LiteratureReference:452731] Octamer and Sox elements are required for transcriptional cis regulation of Nanog gene expression
[LiteratureReference:480361] High-throughput biochemical analysis of in vivo location data reveals novel distinct classes of POU5F1(Oct4)/DNA complexes
modified[InstanceEdit:480941] May, B, 2010-01-27
[InstanceEdit:1112614] May, B, 2010-12-06
[InstanceEdit:1475441] May, B, 2011-08-09
[InstanceEdit:2888996] May, B, 2012-12-31
[InstanceEdit:2892234] May, B, 2012-12-31
[InstanceEdit:3108239] May, B, 2013-02-10
[InstanceEdit:5159238] D'Eustachio, P, 2013-11-22
[InstanceEdit:8939408] May, Bruce, 2016-09-18
namePOU5F1:SOX2:NANOG:KLF4:PBX1:SMAD2:FOXP1-ES:NANOG gene
OCT4:SOX2:NANOG:KLF4:PBX1:SMAD2:FOXP1-ES:NANOG gene
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:5649019] R-HSA-480463.2
summation[Summation:480635] KLF4, PBX1, OCT4 (POU5F1), SOX2, and NANOG bind the promoter...
(output)[Reaction:480204] POU5F1 (OCT4), SOX2, NANOG, KLF4, PBX1, SMAD2 bind the NANOG promoter [Homo sapiens]
(regulator)[PositiveGeneExpressionRegulation:5638456] Positive gene expression regulation by 'POU5F1:SOX2:NANOG:KLF4:PBX1:SMAD2:FOXP1-ES:NANOG gene [nucleoplasm]'
(updatedInstance)[_UpdateTracker:9894746] Update Tracker - [Complex:480463] POU5F1:SOX2:NANOG:KLF4:PBX1:SMAD2:FOXP1-ES:NANOG gene [nucleoplasm] - v57:[updateContainedComponent]
[_UpdateTracker:9895257] Update Tracker - [Complex:480463] POU5F1:SOX2:NANOG:KLF4:PBX1:SMAD2:FOXP1-ES:NANOG gene [nucleoplasm] - v59:[addHasComponent, modifyName]
[_UpdateTracker:9902416] Update Tracker - [Complex:480463] POU5F1:SOX2:NANOG:KLF4:PBX1:SMAD2:FOXP1-ES:NANOG gene [nucleoplasm] - v78:[updateContainedComponent]
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No pathways have been reviewed or authored by POU5F1:SOX2:NANOG:KLF4:PBX1:SMAD2:FOXP1-ES:NANOG gene [nucleoplasm] (480463)