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Details on Person Expression of SET

Class:Id	BlackBoxEvent:480435
_displayName	Expression of SET
_timestamp	2018-10-31 14:34:21
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:480249] May, B, 2010-01-27
isChimeric	FALSE
literatureReference	[LiteratureReference:480279] Replication factor encoded by a putative oncogene, set, associated with myeloid leukemogenesis [LiteratureReference:480414] Expression of SET, an inhibitor of protein phosphatase 2A, in renal development and Wilms' tumor [LiteratureReference:480388] Expression of SET is modulated as a function of cell proliferation [LiteratureReference:452962] Regulation of self-renewal and pluripotency by Sox2 in human embryonic stem cells
modified	[InstanceEdit:480941] May, B, 2010-01-27 [InstanceEdit:561173] May, B, 2010-03-30 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9627001] May, Bruce, 2018-10-31 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9733355] Wu, Guanming, 2021-06-04
name	Expression of SET
output	[EntityWithAccessionedSequence:451201] SET [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:480685] POU5F1 (OCT4), SOX2, NANOG bind the SOX2 promoter [Homo sapiens] [BlackBoxEvent:452838] Expression of NANOG [Homo sapiens] [BlackBoxEvent:452894] Expression of SOX2 [Homo sapiens] [BlackBoxEvent:2889036] Translation of OCT4 mRNA [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:480936] Positive gene expression regulation by 'POU5F1:SOX2:NANOG:SOX2 gene [nucleoplasm]'
regulationReference	[RegulationReference:9641950] Positive gene expression regulation by 'POU5F1:SOX2:NANOG:SOX2 gene [nucleoplasm]' Core transcriptional regulatory circuitry in human embryonic stem cells
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8917174] R-HSA-480435.1
summation	[Summation:480615] The SET gene is transcribed to yield mRNA and the mRNA is tr... [Summation:480982] OCT4 (POU5F1), SOX2, and NANOG bind the promoter of the SET ...
(hasEvent)	[Pathway:500407] Individual Binding Reactions and Reactions Regulated by Pluripotency Factors [Homo sapiens]
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No pathways have been reviewed or authored by Expression of SET (480435)