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Details on Person p-S303,307-HSF1 binds YWHAE (14-3-3)

Class:Id	Reaction:4793925
_displayName	p-S303,307-HSF1 binds YWHAE (14-3-3)
_doRelease	TRUE
_timestamp	2014-11-20 02:39:48
authored	[InstanceEdit:4793943] Shamovsky, V, 2013-10-28
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:4793920] Shamovsky, V, 2013-10-28
edited	[InstanceEdit:5324627] Shamovsky, V, 2014-02-17
input	[Complex:194364] YWHAE dimer [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:4793922] p-S303,307-HSF1 [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:4793902] Regulation of molecular chaperone gene transcription involves the serine phosphorylation, 14-3-3 epsilon binding, and cytoplasmic sequestration of heat shock factor 1 [LiteratureReference:4793873] Interactions between extracellular signal-regulated protein kinase 1, 14-3-3epsilon, and heat shock factor 1 during stress
modified	[InstanceEdit:5082424] Shamovsky, V, 2013-11-05 [InstanceEdit:5083129] Shamovsky, V, 2013-11-05 [InstanceEdit:5096439] Shamovsky, V, 2013-11-09 [InstanceEdit:5097242] Shamovsky, V, 2013-11-11 [InstanceEdit:5148862] Shamovsky, V, 2013-11-18 [InstanceEdit:5324681] Shamovsky, V, 2014-02-17 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	p-S303,307-HSF1 binds YWHAE (14-3-3)
output	[Complex:4793921] p-S303,307-HSF1:YWHAE [cytosol] [Homo sapiens]
precedingEvent	[Reaction:3371531] Constitutive phosphorylation by pERK1/2 [Homo sapiens] [Reaction:3371435] Constitutive phosphorylation by GSK3 [Homo sapiens]
releaseDate	2014-03-12
reviewed	[InstanceEdit:5324628] Pani, Bibhusita, 2014-02-17
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5644521] R-HSA-4793925.2
summation	[Summation:5096430] YWHAE (14-3-3epsilon) was found to bind directly to HSF1 and...
(hasEvent)	[Pathway:3371453] Regulation of HSF1-mediated heat shock response [Homo sapiens]
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No pathways have been reviewed or authored by p-S303,307-HSF1 binds YWHAE (14-3-3) (4793925)