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Details on Person Cytosolic phosphoglucomutase (PGM) catalyses the reversible ...

Class:IdSummation:469646
_displayNameCytosolic phosphoglucomutase (PGM) catalyses the reversible ...
_timestamp2017-01-12 16:04:31
created[InstanceEdit:469645] D'Eustachio, P, 2010-01-25
modified[InstanceEdit:469647] D'Eustachio, P, 2010-01-25
[InstanceEdit:917688] D'Eustachio, P, 2010-07-29
[InstanceEdit:5609969] Jassal, Bijay, 2014-07-18
[InstanceEdit:5610088] Jassal, Bijay, 2014-07-21
[InstanceEdit:5690643] Jassal, Bijay, 2015-04-30
[InstanceEdit:8955669] Jassal, Bijay, 2017-01-12
textCytosolic phosphoglucomutase (PGM) catalyses the reversible conversion of glucose 6-phosphate (G6P) to glucose 1-phosphate (G1P) (Drago et al. 1991). Two PGM isoenzymes, both monomers, have been identified which both require Mg2+ as cofactor. PGM1 is the major form found in most tissues except erythrocytes, where PGM2 is abundant (March et al. 1993; Parrington et al. 1968; Putt et al. 1993). PGM2 also has substantial phosphopentomutase activity (Maliekal et al. 2007) and its primary physiological in normal tissues in vivo is not clear. Cytosolic glucose 1,6-bisphosphate synthase (PGM2L1) also possesses phosphoglucomutase activity (Maliekal et al. 2007, Veiga-da-Cunha et al. 2008).
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