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Details on Person CBX4 (Pc2) SUMOylates HNRNPK with SUMO2

Class:IdReaction:4570499
_displayNameCBX4 (Pc2) SUMOylates HNRNPK with SUMO2
_doReleaseTRUE
_timestamp2019-04-08 08:23:06
authored[InstanceEdit:4568916] May, B, 2013-09-19
catalystActivity[CatalystActivity:3108185] SUMO transferase activity of PRC1 complex [nucleoplasm]
catalystActivityReference[CatalystActivityReference:9644136] SUMO transferase activity of PRC1 complex [nucleoplasm] The polycomb protein Pc2 is a SUMO E3
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:4570472] May, B, 2013-09-21
edited[InstanceEdit:4568916] May, B, 2013-09-19
input[EntityWithAccessionedSequence:71945] HNRNPK [nucleoplasm] [Homo sapiens]
[Complex:2993778] SUMO2:UBE2I [nucleoplasm] [Homo sapiens]
[Complex:2993778] SUMO2:UBE2I [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:4570522] DNA damage-induced heterogeneous nuclear ribonucleoprotein K sumoylation regulates p53 transcriptional activation
[LiteratureReference:4570525] Sumoylation of heterogeneous nuclear ribonucleoproteins, zinc finger proteins, and nuclear pore complex proteins: a proteomic analysis
[LiteratureReference:5626896] Uncovering global SUMOylation signaling networks in a site-specific manner
[LiteratureReference:5626900] Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli
[LiteratureReference:5627513] Proteome-wide identification of SUMO2 modification sites
[LiteratureReference:6805075] SUMOylation of hnRNP-K is required for p53-mediated cell-cycle arrest in response to DNA damage
modified[InstanceEdit:5626908] May, Bruce, 2014-10-13
[InstanceEdit:5627522] May, Bruce, 2014-10-19
[InstanceEdit:6805081] May, Bruce, 2015-10-17
[InstanceEdit:9644137] May, Bruce, 2019-04-08
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameCBX4 (Pc2) SUMOylates HNRNPK with SUMO2
output[EntityWithAccessionedSequence:4570532] polySUMO2-K422-HNRNPK [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:912481] UBE2I [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:912481] UBE2I [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2015-12-15
releaseStatusNEW
reviewed[InstanceEdit:6805077] Filosa, Giuseppe, Bachi, Angela, 2015-10-17
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:6812335] R-HSA-4570499.3
summation[Summation:4570465] CBX4 (Pc2) SUMOylates HNRNPK at lysine-422 with SUMO2 (Li et...
(hasEvent)[Pathway:4570464] SUMOylation of RNA binding proteins [Homo sapiens]
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