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Details on Person CBX4 SUMOylates BMI1 in PRC1 with SUMO1
Class:Id Reaction:4551655
_displayName CBX4 SUMOylates BMI1 in PRC1 with SUMO1
_doRelease TRUE
_timestamp 2019-04-08 08:23:20
authored [InstanceEdit:4551677] May, B, 2013-09-13
catalystActivity [CatalystActivity:3108185] SUMO transferase activity of PRC1 complex [nucleoplasm]
catalystActivityReference [CatalystActivityReference:9644136] SUMO transferase activity of PRC1 complex [nucleoplasm] The polycomb protein Pc2 is a SUMO E3
compartment [Compartment:7660] nucleoplasm
created [InstanceEdit:4551601] May, B, 2013-09-14
edited [InstanceEdit:4551677] May, B, 2013-09-13
input [Complex:389114] PRC1 complex [nucleoplasm] [Homo sapiens] [Complex:2993783] SUMO1:C93-UBE2I [nucleoplasm] [Homo sapiens]
isChimeric FALSE
literatureReference [LiteratureReference:4551647] CBX4-mediated SUMO modification regulates BMI1 recruitment at sites of DNA damage
modified [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:8933464] May, Bruce, 2016-08-04 [InstanceEdit:8934412] May, Bruce, 2016-08-09 [InstanceEdit:8956388] May, Bruce, 2017-01-22 [InstanceEdit:9644137] May, Bruce, 2019-04-08 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name CBX4 SUMOylates BMI1 in PRC1 with SUMO1
output [Complex:4551667] monoSUMO1-BMI1:PRC1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:912481] UBE2I [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate 2017-03-27
reviewed [InstanceEdit:8956382] Lu, Jian, 2017-01-22 [InstanceEdit:8956359] Matunis, Michael J, 2017-01-22 [InstanceEdit:8956371] Yang, Wei-Chih, 2017-01-22
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:8894895] R-HSA-4551655.3
summation [Summation:4551669] CBX4 SUMOylates BMI1 in Polycomb Repressive Complex 1 (PRC1)...
(hasEvent) [Pathway:4551638] SUMOylation of chromatin organization proteins [Homo sapiens]
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No pathways have been reviewed or authored by CBX4 SUMOylates BMI1 in PRC1 with SUMO1 (4551655)