Query author contributions in Reactome Reactome depends on collaboration between our curation team and outside experts to
assemble and peer-review its pathway modules. The integration of ORCID within Reactome
enables us to meet a key challenge with authoring, curating and reviewing biological
information by incentivizing and crediting the external experts that contribute their
expertise and time to the Reactome curation process. More information is available at
ORCID and Reactome .
If you have an ORCID ID that is not listed on this page, please
forward this information to us and we will update your Reactome pathway records.
Details on Person SUMOylation of TDG with SUMO1
Class:Id Reaction:4551648 _displayName SUMOylation of TDG with SUMO1 _doRelease TRUE _timestamp 2022-01-19 16:49:41 authored [InstanceEdit:4551677] May, B, 2013-09-13 catalystActivity [CatalystActivity:2997650] SUMO transferase activity of SUMO1:C93-UBE2I [nucleoplasm] catalystActivityReference [CatalystActivityReference:9644118] SUMO transferase activity of SUMO1:C93-UBE2I [nucleoplasm] Identification of a substrate recognition site on Ubc9 compartment [Compartment:7660] nucleoplasm created [InstanceEdit:4551601] May, B, 2013-09-14 edited [InstanceEdit:4551677] May, B, 2013-09-13 input [EntityWithAccessionedSequence:65812] TDG [nucleoplasm] [Homo sapiens] [Complex:2993783] SUMO1:C93-UBE2I [nucleoplasm] [Homo sapiens] isChimeric FALSE literatureReference [LiteratureReference:4551707] Modification of the human thymine-DNA glycosylase by ubiquitin-like proteins facilitates enzymatic turnover [LiteratureReference:4551646] Functionality of human thymine DNA glycosylase requires SUMO-regulated changes in protein conformation [LiteratureReference:4085361] Ubc9 sumoylation regulates SUMO target discrimination [LiteratureReference:4551701] Crystal structure of thymine DNA glycosylase conjugated to SUMO-1 [LiteratureReference:5676992] SUMO-1 regulates the conformational dynamics of thymine-DNA Glycosylase regulatory domain and competes with its DNA binding activity modified [InstanceEdit:4663810] May, B, 2013-10-06 [InstanceEdit:5655630] May, Bruce, 2014-12-07 [InstanceEdit:5677004] May, Bruce, 2015-02-21 [InstanceEdit:9644119] May, Bruce, 2019-04-08 [InstanceEdit:9762281] May, Bruce, 2022-01-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 name SUMOylation of TDG with SUMO1 output [EntityWithAccessionedSequence:912481] UBE2I [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:4551718] monoSUMO1-K330-TDG [nucleoplasm] [Homo sapiens] precedingEvent
releaseDate 2015-03-19 reviewed [InstanceEdit:5677000] Ferrari, Stefano, 2015-02-21 reviewStatus [ReviewStatus:9821382] five stars species [Species:48887] Homo sapiens stableIdentifier [StableIdentifier:5680226] R-HSA-4551648.4 summation [Summation:4551611] TDG is SUMOylated at lysine-330 with SUMO1 by UBE2I (Hardel... (hasEvent) [Pathway:3108214] SUMOylation of DNA damage response and repair proteins [Homo sapiens] (updatedInstance) [_UpdateTracker:9775235] Update Tracker - [Reaction:4551648] SUMOylation of TDG with SUMO1 - v80:[add_removeOutput]
[Change default viewing format]
List...
Protein identifiers
ChEBI identifiers
KEGG COMPOUND identifiers
No pathways have been reviewed or authored by SUMOylation of TDG with SUMO1 (4551648)
