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Details on Person Translocation of NFATC1:CaN:CaM to nucleus

Class:Id	BlackBoxEvent:4551465
_displayName	Translocation of NFATC1:CaN:CaM to nucleus
_doRelease	TRUE
_timestamp	2015-06-09 18:37:35
authored	[InstanceEdit:4551565] Rothfels, K, 2013-09-13
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:4551450] Rothfels, K, 2013-09-13
edited	[InstanceEdit:4663813] Matthews, L, 2013-10-07
input	[Complex:4551448] NFATC1:CaN:CaM [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:2025907] Concerted dephosphorylation of the transcription factor NFAT1 induces a conformational switch that regulates transcriptional activity [LiteratureReference:2685136] Transcriptional regulation by calcium, calcineurin, and NFAT [LiteratureReference:3965320] The Wnt/calcium pathway activates NF-AT and promotes ventral cell fate in Xenopus embryos [LiteratureReference:3965328] Wnt-5a/Ca2+-induced NFAT activity is counteracted by Wnt-5a/Yes-Cdc42-casein kinase 1alpha signaling in human mammary epithelial cells
modified	[InstanceEdit:4610796] Rothfels, K, 2013-09-23 [InstanceEdit:5097368] Rothfels, K, 2013-11-11 [InstanceEdit:5144161] Rothfels, K, 2013-11-15 [InstanceEdit:6782938] Rothfels, Karen, 2015-06-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Translocation of NFATC1:CaN:CaM to nucleus
output	[Complex:4551463] NFATC1:CaN:CaM [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:4551451] Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling [Homo sapiens] [Reaction:2730872] Activation of Calcineurin [Homo sapiens]
releaseDate	2013-12-04
reviewed	[InstanceEdit:5099870] Kikuchi, Akira, 2013-11-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5644668] R-HSA-4551465.3
summation	[Summation:4551464] Dephosphorylated NFAT-calcineurin (CaN) complex translocates...
(hasEvent)	[Pathway:4086398] Ca2+ pathway [Homo sapiens]
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No pathways have been reviewed or authored by Translocation of NFATC1:CaN:CaM to nucleus (4551465)