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Details on Person Prkg is activated upon cGMP binding

Class:Id	Reaction:4551446
_displayName	Prkg is activated upon cGMP binding
_doRelease	TRUE
_timestamp	2014-11-20 02:29:12
authored	[InstanceEdit:4539768] Rothfels, K, 2013-09-03
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:4551450] Rothfels, K, 2013-09-13
edited	[InstanceEdit:4663813] Matthews, L, 2013-10-07
input	[CandidateSet:4551447] Prkg dimer [cytosol] [Mus musculus] [SimpleEntity:30991] cGMP [cytosol] [SimpleEntity:30991] cGMP [cytosol] [SimpleEntity:30991] cGMP [cytosol] [SimpleEntity:30991] cGMP [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:418398] The biology of cyclic GMP-dependent protein kinases [LiteratureReference:4086380] Suppression of cyclic GMP-dependent protein kinase is essential to the Wnt/cGMP/Ca2+ pathway [LiteratureReference:4086381] Signaling of rat Frizzled-2 through phosphodiesterase and cyclic GMP
modified	[InstanceEdit:4551524] Rothfels, K, 2013-09-13 [InstanceEdit:5097285] Rothfels, K, 2013-11-11 [InstanceEdit:5144504] Rothfels, K, 2013-11-15 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Prkg is activated upon cGMP binding
output	[Complex:4551452] Prkg homodimer:cGMP [cytosol] [Mus musculus]
releaseDate	2013-12-04
reviewed	[InstanceEdit:5099870] Kikuchi, Akira, 2013-11-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:5644159] R-MMU-4551446.2
summation	[Summation:4551449] PKG is activated when homodimers bind cGMP, resulting in a c...
(inferredFrom)	[Reaction:4551453] PRKG is activated by binding to high levels of cGMP in the absence of WNT signaling [Homo sapiens]
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No pathways have been reviewed or authored by Prkg is activated upon cGMP binding (4551446)