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Details on Person PIAS1,3 SUMOylates NR5A1 with SUMO2

Class:Id	Reaction:4546385
_displayName	PIAS1,3 SUMOylates NR5A1 with SUMO2
_doRelease	TRUE
_timestamp	2018-08-08 19:30:52
authored	[InstanceEdit:4341133] May, B, 2013-08-18
catalystActivity	[CatalystActivity:4086046] SUMO transferase activity of PIAS1,3 [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:4546388] May, B, 2013-09-05
edited	[InstanceEdit:4341133] May, B, 2013-08-18
input	[EntityWithAccessionedSequence:452955] NR5A1 [nucleoplasm] [Homo sapiens] [Complex:2993778] SUMO2:UBE2I [nucleoplasm] [Homo sapiens] [Complex:2993778] SUMO2:UBE2I [nucleoplasm] [Homo sapiens] [Complex:2993778] SUMO2:UBE2I [nucleoplasm] [Homo sapiens] [Complex:2993778] SUMO2:UBE2I [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:4546348] Small ubiquitin-like modifier 1 (SUMO-1) modification of the synergy control motif of Ad4 binding protein/steroidogenic factor 1 (Ad4BP/SF-1) regulates synergistic transcription between Ad4BP/SF-1 and Sox9 [LiteratureReference:4546359] SUMO modification of repression domains modulates function of nuclear receptor 5A1 (steroidogenic factor-1) [LiteratureReference:4546346] Coactivation of SF-1-mediated transcription of steroidogenic enzymes by Ubc9 and PIAS1
modified	[InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9608079] May, Bruce, 2018-05-09 [InstanceEdit:9615866] May, Bruce, 2018-08-08 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	PIAS1,3 SUMOylates NR5A1 with SUMO2
output	[EntityWithAccessionedSequence:4546383] polySUMO2-K119,K194-NR5A1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:912481] UBE2I [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:912481] UBE2I [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:912481] UBE2I [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:912481] UBE2I [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:2993790] Transfer of SUMO2 from E1 to UBE2I (UBC9) [Homo sapiens] [Reaction:2993784] Conjugation of SUMO2 to UBA2:SAE1 [Homo sapiens]
releaseDate	2018-06-12
reviewed	[InstanceEdit:9608076] Niskanen, Einari, 2018-05-09 [InstanceEdit:9615865] Niskanen, Einari, 2018-08-08
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8930853] R-HSA-4546385.3
summation	[Summation:4546343] PIAS1,3 SUMOylate NR5A1 (Steroidogenic factor 1, SF1, SF-1) ...
(hasEvent)	[Pathway:4090294] SUMOylation of intracellular receptors [Homo sapiens]
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No pathways have been reviewed or authored by PIAS1,3 SUMOylates NR5A1 with SUMO2 (4546385)