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Details on Person PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP

Class:Id	Reaction:453338
_displayName	PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP
_doRelease	TRUE
_timestamp	2026-02-27 17:33:54
authored	[InstanceEdit:453329] D'Eustachio, P, 2010-01-21
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:453352] D'Eustachio, P, 2010-01-21
input	[Complex:453344] PYGM b dimer:AMP [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:453326] Activation of human liver glycogen phosphorylase by alteration of the secondary structure and packing of the catalytic core
modified	[InstanceEdit:453376] D'Eustachio, P, 2010-01-21 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9772993] D'Eustachio, Peter, 2022-04-25 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9931474] D'Eustachio, Peter, 2024-12-11 [InstanceEdit:9983805] D'Eustachio, Peter, 2026-02-27
name	PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP
negativePrecedingEvent	[NegativePrecedingEvent:9983804] Futile Cycle: PYGM dimer, b form + 2 AMP => PYGM b dimer:AMP complex
output	[Complex:71538] PYGM dimer, b form [cytosol] [Homo sapiens] [SimpleEntity:76577] AMP [cytosol] [SimpleEntity:76577] AMP [cytosol]
releaseDate	2010-03-16
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1104587] R-HSA-453338.6
summation	[Summation:453335] Cytosolic, non-phosphorylated PGYM dimers (b form) complexed...
(hasEvent)	[Pathway:70221] Glycogen breakdown (glycogenolysis) [Homo sapiens]
(inferredFrom)	[Reaction:453346] PYGB b dimer:AMP complex => PGYB dimer, b form + 2 AMP [Homo sapiens]
(precedingEvent)	[NegativePrecedingEvent:9931446] Different Cell Type: PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP [Reaction:71541] glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP [Homo sapiens] [Reaction:453342] PYGM dimer, b form + 2 AMP => PYGM b dimer:AMP complex [Homo sapiens]
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No pathways have been reviewed or authored by PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP (453338)