Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person p-Y348-SYK dissociates

Class:IdReaction:453183
_displayNamep-Y348-SYK dissociates
_doReleaseTRUE
_timestamp2015-07-28 14:28:30
authored[InstanceEdit:435013] Akkerman, JW, 2009-09-04
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:453180] Jupe, S, 2010-01-19
edited[InstanceEdit:870306] Jupe, S, 2010-06-07
input[Complex:453171] GPVI:phosphorylated Fc Epsilon R1 gamma:FYN:LYN:Collagen type I:p-Y348-SYK [plasma membrane] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:453173] Syk, activated by cross-linking the B-cell antigen receptor, localizes to the cytosol where it interacts with and phosphorylates alpha-tubulin on tyrosine
modified[InstanceEdit:870420] Jupe, S, 2010-06-08
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:6788924] Jupe, Steve, 2015-07-28
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namep-Y348-SYK dissociates
output[Complex:434822] GPVI:phosphorylated Fc Epsilon R1 gamma:FYN:LYN:Collagen type I [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:437953] p-Y348-SYK [cytosol] [Homo sapiens]
precedingEvent
releaseDate2010-09-21
reviewed[InstanceEdit:870290] Kunapuli, SP, 2010-06-07
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1105027] R-HSA-453183.3
summation[Summation:453172] Structural and biophysical studies indicate that the adaptab...
(hasEvent)[Pathway:114604] GPVI-mediated activation cascade [Homo sapiens]
(precedingEvent)[Reaction:429449] Syk activation leads to SLP-76 activation [Homo sapiens]
[Reaction:434836] Syk/Lck phosphorylate LAT [Homo sapiens]
[Reaction:437932] p-Y348-SYK binds VAV family [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by p-Y348-SYK dissociates (453183)