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Details on Person GATA6 [nucleoplasm]
Class:Id EntityWithAccessionedSequence:452902
_displayName GATA6 [nucleoplasm]
_timestamp 2011-08-12 16:33:58
compartment [Compartment:7660] nucleoplasm
created [InstanceEdit:452990] May, B, 2010-01-15
endCoordinate 595
modified [InstanceEdit:1485617] May, B, 2011-08-12 [InstanceEdit:3448660] Wu, G, 2013-05-16
name GATA6 Transcription factor GATA-6 GATA6_HUMAN
referenceEntity [ReferenceGeneProduct:55344] UniProt:Q92908 GATA6 [Homo sapiens]
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:1109313] R-HSA-452902.1
startCoordinate 1
(hasComponent) [Complex:5683868] LMCD1:GATA6 [nucleoplasm] [Homo sapiens] [Complex:5685293] GATA6:SFTPAs [nucleoplasm] [Homo sapiens] [Complex:9735252] GATA4:GATA6:ISL1:LDB1:HAND2 gene [nucleoplasm] [Homo sapiens] [Complex:9823744] TCF7L2:CTNNB1:EOMES:TBXT:MIXL1:p-2S-SMAD2,3:SMAD4:FOXA2:GATA4:GATA6,SOX17 gene [nucleoplasm] [Homo sapiens] [Complex:9823834] p-2S-SMAD2,3:SMAD4:FOXA2:TBXT:GATA6:GATA4 gene [nucleoplasm] [Homo sapiens] [Complex:9823963] EOMES:TBXT:GATA6:p-2S-SMAD2,3:SMAD4:FOXA2 gene [nucleoplasm] [Homo sapiens] [Complex:9823975] EOMES:p-2S-SMAD2,3:SMAD4:GATA6:CXCR4 gene [nucleoplasm] [Homo sapiens] [Complex:9823994] EOMES:p-2S-SMAD2,3:SMAD4:GATA6:LHX1 gene [nucleoplasm] [Homo sapiens]
(hasMember) [DefinedSet:500380] Proteins Encoded by Genes Repressed by OCT4:NANOG [nucleoplasm] [Homo sapiens] [DefinedSet:996770] GATA proteins [nucleoplasm] [Homo sapiens] [DefinedSet:9749908] GATA4,6 [nucleoplasm] [Homo sapiens]
(input) [Reaction:5683888] LMCD1 binds GATA6, sequestering it [Homo sapiens] [Reaction:5685296] GATA6 binds SFTPA genes [Homo sapiens] [Reaction:9735302] GATA4, GATA6, and ISL1:LDB1 bind the HAND2 gene [Homo sapiens] [Reaction:9823836] SMAD2,3, FOXA2, TBXT, and GATA6 bind the GATA4 gene [Homo sapiens] [Reaction:9823952] EOMES, SMAD2,3, and GATA6 bind the CXCR4 gene [Homo sapiens] [Reaction:9823958] EOMES, TBXT (T BRACHYURY), GATA6, and SMAD2,3 bind the FOXA2 gene [Homo sapiens] [Reaction:9823964] EOMES, SMAD2,3, and GATA6 bind the LHX1 gene [Homo sapiens] [Reaction:9824472] TCF7L2:CTNNB1, EOMES, TBXT, MIXL1, SMAD2,3, FOXA2, GATA4, and GATA6 bind the SOX17 gene [Homo sapiens]
(marker) [MarkerReference:9927540] GATA6 [nucleoplasm] GATA6 is essential for endoderm formation from human pluripotent stem cells
(output) [BlackBoxEvent:452572] Expression of GATA6 [Homo sapiens] [BlackBoxEvent:9734573] Expression of GATA6 in cardiogenesis [Homo sapiens] [BlackBoxEvent:9823977] Expression of GATA6 in definitive endoderm [Homo sapiens]
(proteinMarker) [Cell:9911207] definitive endoderm cell [Homo sapiens]
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Pathways
No pathways have been reviewed or authored by GATA6 [nucleoplasm] (452902)