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Details on Person Expression of Histone H4 (HIST1H4E)

Class:Id	BlackBoxEvent:452883
_displayName	Expression of Histone H4 (HIST1H4E)
_timestamp	2018-10-31 14:07:53
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:452990] May, B, 2010-01-15
isChimeric	FALSE
literatureReference	[LiteratureReference:452628] Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells [LiteratureReference:452250] Mass spectrometry identifies and quantifies 74 unique histone H4 isoforms in differentiating human embryonic stem cells [LiteratureReference:452661] Establishment of histone gene regulation and cell cycle checkpoint control in human embryonic stem cells [LiteratureReference:111696] The human and mouse replication-dependent histone genes
modified	[InstanceEdit:561173] May, B, 2010-03-30 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9626994] May, Bruce, 2018-10-31 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9733355] Wu, Guanming, 2021-06-04
name	Expression of Histone H4 (HIST1H4E)
output	[EntityWithAccessionedSequence:181902] HIST1H4 [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:480685] POU5F1 (OCT4), SOX2, NANOG bind the SOX2 promoter [Homo sapiens] [BlackBoxEvent:452838] Expression of NANOG [Homo sapiens] [BlackBoxEvent:452894] Expression of SOX2 [Homo sapiens] [BlackBoxEvent:2889036] Translation of OCT4 mRNA [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:452262] Positive gene expression regulation by 'POU5F1:SOX2:NANOG:SOX2 gene [nucleoplasm]'
regulationReference	[RegulationReference:9641322] Positive gene expression regulation by 'POU5F1:SOX2:NANOG:SOX2 gene [nucleoplasm]' Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8914092] R-HSA-452883.1
summation	[Summation:452719] The HIST1H4E gene is a member of the family of genes that en... [Summation:452202] OCT4 (POU5F1) binds the promoter of the HIST1H4E gene, one o...
(hasEvent)	[Pathway:500407] Individual Binding Reactions and Reactions Regulated by Pluripotency Factors [Homo sapiens]
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No pathways have been reviewed or authored by Expression of Histone H4 (HIST1H4E) (452883)