Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person Expression of Dickkopf-1 (DKK1)

Class:Id	BlackBoxEvent:452875
_displayName	Expression of Dickkopf-1 (DKK1)
_doRelease	FALSE
_timestamp	2018-10-31 13:52:07
authored	[InstanceEdit:1013049] May, B, 2010-11-12
compartment	[Compartment:7660] nucleoplasm [Compartment:984] extracellular region
created	[InstanceEdit:452990] May, B, 2010-01-15
edited	[InstanceEdit:1013049] May, B, 2010-11-12
input	[EntityWithAccessionedSequence:2888959] DKK1 gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:452611] Olig2-induced neural stem cell differentiation involves downregulation of Wnt signaling and induction of Dickkopf-1 expression [LiteratureReference:452933] Dickkopf-1 expression increases early in prostate cancer development and decreases during progression from primary tumor to metastasis [LiteratureReference:452965] The Wnt antagonist Dickkopf-1 and its receptors are coordinately regulated during early human adipogenesis [LiteratureReference:452678] Dickkopf-1, an inhibitor of Wnt signaling, is regulated by progesterone in human endometrial stromal cells [LiteratureReference:452270] The Wnt antagonist DICKKOPF-1 gene is a downstream target of beta-catenin/TCF and is downregulated in human colon cancer [LiteratureReference:452340] Dickkopf-1, an inhibitor of the Wnt signaling pathway, is induced by p53 [LiteratureReference:452628] Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells [LiteratureReference:452538] Core transcriptional regulatory circuitry in human embryonic stem cells [LiteratureReference:452948] In silico identification of a core regulatory network of OCT4 in human embryonic stem cells using an integrated approach
modified	[InstanceEdit:1013055] May, B, 2010-11-12 [InstanceEdit:1080832] May, B, 2010-11-29 [InstanceEdit:1086967] May, B, 2010-11-29 [InstanceEdit:1101836] May, B, 2010-12-01 [InstanceEdit:2892244] May, B, 2012-12-31 [InstanceEdit:3108239] May, B, 2013-02-10 [InstanceEdit:3165216] May, B, 2013-02-22 [InstanceEdit:4411347] May, B, 2013-08-23 [InstanceEdit:4420242] May, B, 2013-08-31 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9626991] May, Bruce, 2018-10-31 [InstanceEdit:9641190] Wu, G, 2019-04-04
name	Expression of Dickkopf-1 (DKK1)
output	[EntityWithAccessionedSequence:452535] DKK1 [extracellular region] [Homo sapiens]
regulatedBy	[NegativeGeneExpressionRegulation:5163265] Negative gene expression regulation by 'POU5F1:SOX2:NANOG:DKK1 gene [nucleoplasm]'
regulationReference	[RegulationReference:9642940] Negative gene expression regulation by 'POU5F1:SOX2:NANOG:DKK1 gene [nucleoplasm]' Core transcriptional regulatory circuitry in human embryonic stem cells
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8901858] R-HSA-452875.1
summation	[Summation:452595] The Dickkopf-1 (DKK1) gene is transcribed to yield mRNA and ...
(hasEvent)	[Pathway:500407] Individual Binding Reactions and Reactions Regulated by Pluripotency Factors [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by Expression of Dickkopf-1 (DKK1) (452875)