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Details on Person Expression of FOXD3

Class:Id	BlackBoxEvent:452750
_displayName	Expression of FOXD3
_doRelease	TRUE
_timestamp	2018-10-31 13:58:14
authored	[InstanceEdit:1013049] May, B, 2010-11-12
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:452990] May, B, 2010-01-15
edited	[InstanceEdit:1013049] May, B, 2010-11-12
input	[EntityWithAccessionedSequence:2888992] FOXD3 gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:452628] Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells [LiteratureReference:452538] Core transcriptional regulatory circuitry in human embryonic stem cells [LiteratureReference:1101821] Functional genomics of 5- to 8-cell stage human embryos by blastomere single-cell cDNA analysis [LiteratureReference:2901798] Modulation of FOXD3 activity in human embryonic stem cells directs pluripotency and paraxial mesoderm fates [LiteratureReference:5250252] Transposable elements have rewired the core regulatory network of human embryonic stem cells [LiteratureReference:5251056] Regulation of embryonic stem cell self-renewal and pluripotency by Foxd3
modified	[InstanceEdit:561173] May, B, 2010-03-30 [InstanceEdit:1013055] May, B, 2010-11-12 [InstanceEdit:1086967] May, B, 2010-11-29 [InstanceEdit:1101836] May, B, 2010-12-01 [InstanceEdit:2889038] May, B, 2012-12-31 [InstanceEdit:2901807] May, B, 2013-01-03 [InstanceEdit:2972981] D'Eustachio, P, 2013-01-06 [InstanceEdit:3108239] May, B, 2013-02-10 [InstanceEdit:3165216] May, B, 2013-02-22 [InstanceEdit:4411347] May, B, 2013-08-23 [InstanceEdit:4420242] May, B, 2013-08-31 [InstanceEdit:5250254] May, B, 2014-01-24 [InstanceEdit:5250255] May, B, 2014-01-24 [InstanceEdit:5251098] May, B, 2014-01-31 [InstanceEdit:5638458] May, Bruce, 2014-11-15 [InstanceEdit:6800077] May, Bruce, 2015-09-27 [InstanceEdit:8865030] D'Eustachio, Peter, 2016-03-18 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9626992] May, Bruce, 2018-10-31 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Expression of FOXD3
output	[EntityWithAccessionedSequence:452918] FOXD3 [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:2972964] POU5F1 (OCT4), SOX2, NANOG bind the FOXD3 promoter [Homo sapiens] [BlackBoxEvent:452838] Expression of NANOG [Homo sapiens] [BlackBoxEvent:452894] Expression of SOX2 [Homo sapiens] [BlackBoxEvent:2889036] Translation of OCT4 mRNA [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:5638447] Positive gene expression regulation by 'POU5F1:SOX2:NANOG:FOXD3 gene [nucleoplasm]'
regulationReference	[RegulationReference:9641457] Positive gene expression regulation by 'POU5F1:SOX2:NANOG:FOXD3 gene [nucleoplasm]' Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells
releaseDate	2014-03-12
reviewed	[InstanceEdit:5246708] Wang, Jianlong, 2014-01-22
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5645151] R-HSA-452750.7
summation	[Summation:452518] The Forkhead box protein D3 (FOXD3) gene is transcribed and ...
(hasEvent)	[Pathway:500407] Individual Binding Reactions and Reactions Regulated by Pluripotency Factors [Homo sapiens] [Pathway:2892247] POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9783877] Update Tracker - [BlackBoxEvent:452750] Expression of FOXD3 - v55:[removeCatalystActivity] [_UpdateTracker:9785871] Update Tracker - [BlackBoxEvent:452750] Expression of FOXD3 - v51:[addCatalystActivity, addRegulator, add_removeInput]
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No pathways have been reviewed or authored by Expression of FOXD3 (452750)