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Details on Person Expression of GATA6

Class:IdBlackBoxEvent:452572
_displayNameExpression of GATA6
_doReleaseFALSE
_timestamp2018-10-31 14:01:07
authored[InstanceEdit:1013049] May, B, 2010-11-12
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:452990] May, B, 2010-01-15
edited[InstanceEdit:1013049] May, B, 2010-11-12
input[EntityWithAccessionedSequence:2888975] GATA6 gene [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:452240] The human GATA-6 gene: structure, chromosomal location, and regulation of expression by tissue-specific and mitogen-responsive signals
[LiteratureReference:452721] Molecular cloning of human GATA-6 DNA binding protein: high levels of expression in heart and gut
[LiteratureReference:452968] Distinct functions are implicated for the GATA-4, -5, and -6 transcription factors in the regulation of intestine epithelial cell differentiation
[LiteratureReference:452628] Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells
[LiteratureReference:452538] Core transcriptional regulatory circuitry in human embryonic stem cells
[LiteratureReference:452948] In silico identification of a core regulatory network of OCT4 in human embryonic stem cells using an integrated approach
modified[InstanceEdit:1013055] May, B, 2010-11-12
[InstanceEdit:1086967] May, B, 2010-11-29
[InstanceEdit:1101836] May, B, 2010-12-01
[InstanceEdit:2892244] May, B, 2012-12-31
[InstanceEdit:2895785] May, B, 2013-01-03
[InstanceEdit:3108239] May, B, 2013-02-10
[InstanceEdit:3165216] May, B, 2013-02-22
[InstanceEdit:4411347] May, B, 2013-08-23
[InstanceEdit:4420242] May, B, 2013-08-31
[InstanceEdit:8879177] Wu, G, 2016-07-15
[InstanceEdit:9606200] Wu, G, 2018-04-19
[InstanceEdit:9626993] May, Bruce, 2018-10-31
[InstanceEdit:9641190] Wu, G, 2019-04-04
[InstanceEdit:9733355] Wu, Guanming, 2021-06-04
nameExpression of GATA6
output[EntityWithAccessionedSequence:452902] GATA6 [nucleoplasm] [Homo sapiens]
regulatedBy[NegativeGeneExpressionRegulation:5163270] Negative gene expression regulation by 'POU5F1:NANOG:GATA6 gene [nucleoplasm]'
regulationReference[RegulationReference:9641340] Negative gene expression regulation by 'POU5F1:NANOG:GATA6 gene [nucleoplasm]' Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8923925] R-HSA-452572.1
summation[Summation:452606] The gene encoding Transcription factor GATA-6 (GATA6) is tra...
[Summation:5163262] POU5F1 (OCT4), SOX2, and NANOG bind the GATA6 promoter and r...
(hasEvent)[Pathway:500407] Individual Binding Reactions and Reactions Regulated by Pluripotency Factors [Homo sapiens]
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