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Details on Person SOX2 [nucleoplasm]
Class:Id EntityWithAccessionedSequence:452271 _displayName SOX2 [nucleoplasm] _timestamp 2014-11-20 04:03:12 compartment [Compartment:7660] nucleoplasm created [InstanceEdit:452990] May, B, 2010-01-15 endCoordinate 317 modified [InstanceEdit:3448660] Wu, G, 2013-05-16 name SOX2 referenceEntity [ReferenceGeneProduct:64856] UniProt:P48431 SOX2 [Homo sapiens] species [Species:48887] Homo sapiens stableIdentifier [StableIdentifier:5648049] R-HSA-452271.1 startCoordinate 1 (activeUnit) [PositiveGeneExpressionRegulation:452214] Positive gene expression regulation by 'POU5F1:SOX2:NANOG:DPPA4 gene [nucleoplasm]' [PositiveGeneExpressionRegulation:5638447] Positive gene expression regulation by 'POU5F1:SOX2:NANOG:FOXD3 gene [nucleoplasm]' [PositiveGeneExpressionRegulation:5638448] Positive gene expression regulation by 'POU5F1:SOX2:NANOG:STAT3 gene [nucleoplasm]' [PositiveGeneExpressionRegulation:5638449] Positive gene expression regulation by 'POU5F1:SOX2:NANOG:TDGF1 gene [nucleoplasm]' [PositiveGeneExpressionRegulation:5638452] Positive gene expression regulation by 'POU5F1:SOX2:NANOG:ZSCAN10:PRDM14:SMAD2:SALL4:FOXP1-ES:POU5F1 gene [nucleoplasm]' [PositiveGeneExpressionRegulation:5638453] Positive gene expression regulation by 'POU5F1:SOX2:NANOG:ZIC3 gene [nucleoplasm]' [PositiveGeneExpressionRegulation:5638454] Positive gene expression regulation by 'POU5F1:SOX2:NANOG:SOX2 gene [nucleoplasm]' [PositiveGeneExpressionRegulation:5638455] Positive gene expression regulation by 'POU5F1:SOX2:NANOG:EPHA1 gene [nucleoplasm]' [PositiveGeneExpressionRegulation:5638456] Positive gene expression regulation by 'POU5F1:SOX2:NANOG:KLF4:PBX1:SMAD2:FOXP1-ES:NANOG gene [nucleoplasm]' [PositiveGeneExpressionRegulation:5638457] Positive gene expression regulation by 'POU5F1:SOX2:NANOG:FGF2 gene [nucleoplasm]' (hasComponent) [Complex:480463] POU5F1:SOX2:NANOG:KLF4:PBX1:SMAD2:FOXP1-ES:NANOG gene [nucleoplasm] [Homo sapiens] [Complex:480572] POU5F1:SOX2:NANOG:SOX2 gene [nucleoplasm] [Homo sapiens] [Complex:1112611] POU5F1:SOX2:NANOG:ZSCAN10:PRDM14:SMAD2:SALL4:FOXP1-ES:POU5F1 gene [nucleoplasm] [Homo sapiens] [Complex:2888997] POU5F1:SOX2:PIP5K1C gene [nucleoplasm] [Homo sapiens] [Complex:2888998] POU5F1:SOX2:NANOG:DKK1 gene [nucleoplasm] [Homo sapiens] [Complex:2889000] POU5F1:SOX2:NANOG:EOMES gene [nucleoplasm] [Homo sapiens] [Complex:2889001] POU5F1:SOX2:NANOG:GNG10 gene [nucleoplasm] [Homo sapiens] [Complex:2889002] POU5F1:SOX2:NANOG:TNC gene [nucleoplasm] [Homo sapiens] [Complex:2889003] POU5F1:SOX2:NANOG:STAT3 gene [nucleoplasm] [Homo sapiens] [Complex:2889005] POU5F1:SOX2:NANOG:KDR gene [nucleoplasm] [Homo sapiens] (hasMember) [DefinedSet:5626912] SRY,SOX2,SOX3,SOX4,SOX6,SOX7,SOX9,SOX17 [nucleoplasm] [Homo sapiens] [DefinedSet:6790042] STAT3-upregulated nuclear proteins [nucleoplasm] [Homo sapiens] (input) [Reaction:480204] POU5F1 (OCT4), SOX2, NANOG, KLF4, PBX1, SMAD2 bind the NANOG promoter [Homo sapiens] [Reaction:480685] POU5F1 (OCT4), SOX2, NANOG bind the SOX2 promoter [Homo sapiens] [Reaction:1112609] POU5F1 (OCT4), SOX2, NANOG, ZSCAN10, PRDM14, SMAD2, FOXP1-ES bind the POU5F1 (OCT4) promoter [Homo sapiens] [Reaction:2972946] POU5F1 (OCT4), SOX2, NANOG Bind the TNC Promoter [Homo sapiens] [Reaction:2972947] POU5F1 (OCT4), SOX2, NANOG Bind the ORC1 Promoter [Homo sapiens] [Reaction:2972948] POU5F1 (OCT4), SOX2, NANOG bind the GSC promoter [Homo sapiens] [Reaction:2972949] POU5F1 (OCT4), SOX2, NANOG bind the EOMES promoter [Homo sapiens] [Reaction:2972950] POU5F1 (OCT4), SOX2 Bind the PIP5K1C Promoter [Homo sapiens] [Reaction:2972951] POU5F1 (OCT4), SOX2, NANOG Bind the KDR Promoter [Homo sapiens] [Reaction:2972954] POU5F1 (OCT4), SOX2, NANOG Bind the SFRP2 Promoter [Homo sapiens] (marker) [MarkerReference:9732089] SOX2 [nucleoplasm] Pax3 and Zic1 trigger the early neural crest gene regulatory network by the direct activation of multiple key neural crest specifiers [MarkerReference:9749825] SOX2 [nucleoplasm] Sox2 and Mitf cross-regulatory interactions consolidate progenitor and melanocyte lineages in the cranial neural crest (output) [BlackBoxEvent:452894] Expression of SOX2 [Homo sapiens] [Reaction:9754480] p-2S-SMAD2,3:SMAD4, CTNNB1, and TBPL2 bind FOXH1:SMAD3:EOMES gene [Homo sapiens] [BlackBoxEvent:9832841] Expression of SOX2 in anterior neural plate [Homo sapiens] [BlackBoxEvent:9832988] Expression of SOX2 in posterior neural plate [Homo sapiens] [BlackBoxEvent:9926523] MITF-M-dependent SOX2 gene expression [Homo sapiens] (proteinMarker) [Cell:9732128] premigratory trunk neural crest cell [Homo sapiens] (regulator) [NegativeGeneExpressionRegulation:452360] Negative gene expression regulation by 'SOX2 [nucleoplasm]' [PositiveGeneExpressionRegulation:480928] Positive gene expression regulation by 'SOX2 [nucleoplasm]' [NegativeGeneExpressionRegulation:480952] Negative gene expression regulation by 'SOX2 [nucleoplasm]' [NegativeGeneExpressionRegulation:480963] Negative gene expression regulation by 'SOX2 [nucleoplasm]'
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Pathways
No pathways have been reviewed or authored by SOX2 [nucleoplasm] (452271)
