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Details on Person EOMES [nucleoplasm]
Class:Id EntityWithAccessionedSequence:452232
_displayName EOMES [nucleoplasm]
_timestamp 2016-07-15 23:50:53
compartment [Compartment:7660] nucleoplasm
created [InstanceEdit:452990] May, B, 2010-01-15
endCoordinate 686
modified [InstanceEdit:1485617] May, B, 2011-08-12 [InstanceEdit:3448660] Wu, G, 2013-05-16 [InstanceEdit:8879177] Wu, G, 2016-07-15
name EOMES Eomesodermin homolog EOMES_HUMAN
referenceEntity [ReferenceGeneProduct:54344] UniProt:O95936 EOMES [Homo sapiens]
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:8931184] R-HSA-452232.1
startCoordinate 1
(hasComponent) [Complex:9733794] EOMES:WDR5:KAT2A:TBXT:MESP1 gene [nucleoplasm] [Homo sapiens] [Complex:9756662] EOMES:TBXT:SNAI1 gene [nucleoplasm] [Homo sapiens] [Complex:9756663] EOMES:TBXT:POU5F1 gene [nucleoplasm] [Homo sapiens] [Complex:9756679] EOMES:TBXT:SOX2 gene [nucleoplasm] [Homo sapiens] [Complex:9756683] EOMES:TBXT:NANOG gene [nucleoplasm] [Homo sapiens] [Complex:9756735] p-2S-SMAD2,3:TRIM33:p-2S-SMAD2,3:SMAD4:CTNNB1:FOXH1:EOMES:TBPL2:MIXL1 gene [nucleoplasm] [Homo sapiens] [Complex:9756737] p-2S-SMAD2,3:SMAD4:EOMES:FOXH1:p-2S-SMAD2,3:TRIM33:MIXL1 gene [nucleoplasm] [Homo sapiens] [Complex:9756966] p-2S-SMAD2,3:SMAD4:TRIM33:CTNNB1:FOXH1:SMAD3:EOMES:TBPL2:GSC gene [nucleoplasm] [Homo sapiens] [Complex:9823744] TCF7L2:CTNNB1:EOMES:TBXT:MIXL1:p-2S-SMAD2,3:SMAD4:FOXA2:GATA4:GATA6,SOX17 gene [nucleoplasm] [Homo sapiens] [Complex:9823963] EOMES:TBXT:GATA6:p-2S-SMAD2,3:SMAD4:FOXA2 gene [nucleoplasm] [Homo sapiens]
(hasMember) [DefinedSet:500356] Proteins Encoded by Genes Repressed by OCT4:SOX2:NANOG [nucleoplasm] [Homo sapiens]
(input) [Reaction:9733781] EOMES, WDR5, KAT2A, and TBXT bind the MESP1 gene [Homo sapiens] [Reaction:9756661] EOMES and TBXT bind the SOX2 gene [Homo sapiens] [Reaction:9756666] EOMES and TBXT (T, Brachyury) bind the SNAI1 gene [Homo sapiens] [Reaction:9756670] EOMES and TBXT bind the POU5F1 (OCT4) gene [Homo sapiens] [Reaction:9756671] EOMES and TBXT bind the NANOG gene [Homo sapiens] [Reaction:9756724] p-2S-SMAD2,3:TRIM33, p-2S-SMAD2,3:SMAD4, CTNNB1, EOMES, and TBPL2 bind FOXH1:MIXL1 gene [Homo sapiens] [Reaction:9756948] p-2S-SMAD2,3:SMAD4, p-2S-SMAD2,3:TRIM33, CTNNB1, EOMES, and TBPL2 bind FOXH1:SMAD3:GSC gene [Homo sapiens] [Reaction:9823952] EOMES, SMAD2,3, and GATA6 bind the CXCR4 gene [Homo sapiens] [Reaction:9823958] EOMES, TBXT (T BRACHYURY), GATA6, and SMAD2,3 bind the FOXA2 gene [Homo sapiens] [Reaction:9823964] EOMES, SMAD2,3, and GATA6 bind the LHX1 gene [Homo sapiens]
(output) [BlackBoxEvent:452353] Expression of EOMES in the primitive streak [Homo sapiens]
(regulator) [PositiveGeneExpressionRegulation:9828102] Positive gene expression regulation by 'EOMES [nucleoplasm]'
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Pathways
No pathways have been reviewed or authored by EOMES [nucleoplasm] (452232)