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Details on Person Jupe, S, 2010-01-15
| Class:Id | InstanceEdit:452117 |
| _displayName | Jupe, S, 2010-01-15 |
| _timestamp | 2010-01-15 17:13:08 |
| author | [Person:391309] Jupe, Steve |
| dateTime | 2010-01-15 22:12:27 |
| (created) | [Reaction:452091] Phosphorylation of IL2RB Y338 enables SHC recruitment [Homo sapiens] [LiteratureReference:452092] Evidence for a role for the phosphotyrosine-binding domain of Shc in interleukin 2 signaling [EntityWithAccessionedSequence:452093] p-Y364,Y418,Y536-IL2RB [plasma membrane] [Homo sapiens] [DefinedSet:452094] STAT5A,STAT5B [cytosol] [Homo sapiens] [Complex:452095] IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:SHC [plasma membrane] [Homo sapiens] [Reaction:452097] Recruited STAT5 is phosphorylated [Homo sapiens] [LiteratureReference:452098] Distinct tyrosine residues within the interleukin-2 receptor beta chain drive signal transduction specificity, redundancy, and diversity [Reaction:452099] DO NOT RELEASE - LCK phosphorylates multiple tyrosines of IL2RB [Homo sapiens] [Reaction:452100] SHC1 bound to IL2 receptor is phosphorylated [Homo sapiens] [Person:452101] Migone, TS |
| (modified) | [Pathway:449147] Signaling by Interleukins [Homo sapiens] [Pathway:451927] Interleukin-2 family signaling [Homo sapiens] [Reaction:451942] Within the IL-2R complex JAK3 phosphorylates JAK1 [Homo sapiens] |
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No pathways have been reviewed or authored by Jupe, S, 2010-01-15 (452117)