Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person SHC1 bound to IL2 receptor is phosphorylated

Class:Id	Reaction:452100
_displayName	SHC1 bound to IL2 receptor is phosphorylated
_doRelease	TRUE
_timestamp	2017-12-08 18:26:21
authored	[InstanceEdit:744679] Ray, KP, 2010-05-17
catalystActivity	[CatalystActivity:453091] protein tyrosine kinase activity of SHC kinases in IL2 signaling [cytosol]
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:452117] Jupe, S, 2010-01-15
edited	[InstanceEdit:924611] Jupe, S, 2010-08-06
input	[Complex:452095] IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:SHC [plasma membrane] [Homo sapiens] [SimpleEntity:113592] ATP [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:453090] The adapter protein Shc interacts with the interleukin-2 (IL-2) receptor upon IL-2 stimulation
modified	[InstanceEdit:453095] Jupe, S, 2010-01-18 [InstanceEdit:507917] Jupe, S, 2010-02-09 [InstanceEdit:539069] Jupe, S, 2010-03-09 [InstanceEdit:912541] Jupe, S, 2010-07-09 [InstanceEdit:918253] Jupe, S, 2010-08-02 [InstanceEdit:919403] Jupe, S, 2010-08-04 [InstanceEdit:926765] Jupe, S, 2010-08-06 [InstanceEdit:941875] Jupe, S, 2010-09-06 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:1168657] Jupe, S, 2011-01-05 [InstanceEdit:1213499] Jupe, S, 2011-02-11 [InstanceEdit:1233244] Jupe, S, 2011-03-17 [InstanceEdit:9020559] Duenas, Corina, 2017-09-07 [InstanceEdit:9032272] Orlic-Milacic, Marija, 2017-12-08 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	SHC1 bound to IL2 receptor is phosphorylated
output	[Complex:453099] IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] [Homo sapiens] [SimpleEntity:29370] ADP [cytosol]
precedingEvent	[Reaction:452091] Phosphorylation of IL2RB Y338 enables SHC recruitment [Homo sapiens] [Reaction:452122] JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB [Homo sapiens]
releaseDate	2011-03-15
reviewed	[InstanceEdit:1213492] Villarino, A, 2011-02-11 [InstanceEdit:1233246] Dooms, H, 2011-03-17
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1224911] R-HSA-452100.4
summation	[Summation:453106] Following IL2 stimulation of IL2R, Shc is known to be tyrosi...
(hasEvent)	[Pathway:9020558] Interleukin-2 signaling [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:453104] Phosphorylated SHC1 recruits GRB2:GAB2 [Homo sapiens] [Reaction:453111] Phosphorylated SHC recruits GRB2:SOS1 [Homo sapiens] [Reaction:913374] Phosphorylated SHC1 recruits SHIP [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by SHC1 bound to IL2 receptor is phosphorylated (452100)