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Details on Person Molecular analysis of human argininosuccinate lyase: mutant characterization and alternative splicing of the coding region

Class:Id	LiteratureReference:452031
_displayName	Molecular analysis of human argininosuccinate lyase: mutant characterization and alternative splicing of the coding region
_timestamp	2010-01-14 23:40:08
author	[Person:452037] Walker, DC [Person:452011] McCloskey, DA [Person:452035] Simard, LR [Person:451997] McInnes, RR
created	[InstanceEdit:452030] D'Eustachio, P, 2010-01-14
journal	Proc Natl Acad Sci U S A
modified	[InstanceEdit:452049] D'Eustachio, P, 2010-01-14
pages	9625-9
pubMedIdentifier	2263616
title	Molecular analysis of human argininosuccinate lyase: mutant characterization and alternative splicing of the coding region
volume	87
year	1990
(literatureReference)	[Complex:70571] ASL tetramer [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9959319] ASL R95C [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9959340] ASL D87G [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9959346] ASL Q286R [cytosol] [Homo sapiens] [Reaction:70573] argininosuccinate <=> fumarate + arginine [Homo sapiens] [FailedReaction:9956524] ASL variants don't synthesize fumarate and arginine [Homo sapiens] [Pathway:9956529] ASL variants cause argininosuccinate aciduria [Homo sapiens] [CatalystActivityReference:9643560] argininosuccinate lyase activity of ASL tetramer [cytosol] Molecular analysis of human argininosuccinate lyase: mutant characterization and alternative splicing of the coding region
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