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Details on Person Hierarchy of protein tyrosine kinases in interleukin-2 (IL-2) signaling: activation of syk depends on Jak3; however, neither Syk nor Lck is required for IL-2-mediated STAT activation
| Class:Id | LiteratureReference:451930 |
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| _displayName | Hierarchy of protein tyrosine kinases in interleukin-2 (IL-2) signaling: activation of syk depends on Jak3; however, neither Syk nor Lck is required for IL-2-mediated STAT activation |
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| _timestamp | 2010-01-14 16:52:52 |
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| author | [Person:451923] Zhou, YJ
[Person:451925] Magnuson, KS
[Person:451932] Cheng, TP
[Person:451924] Gadina, M
[Person:451934] Frucht, DM
[Person:451941] Galon, J
[Person:451937] Candotti, F
[Person:451922] Geahlen, RL
[Person:451933] Changelian, PS
[Person:447239] O'Shea, JJ |
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| created | [InstanceEdit:451938] Jupe, S, 2010-01-14 |
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| journal | Mol Cell Biol |
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| pages | 4371-80 |
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| pubMedIdentifier | 10825200 |
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| title | Hierarchy of protein tyrosine kinases in interleukin-2 (IL-2) signaling: activation of syk depends on Jak3; however, neither Syk nor Lck is required for IL-2-mediated STAT activation |
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| volume | 20 |
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| year | 2000 |
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| (literatureReference) | [Summation:539018] DO NOT RELEASE - LCK stably binds to the cytoplasmic acidic ...
[CatalystActivityReference:9643374] protein tyrosine kinase activity of IL2:IL2R trimer:p-JAK1:JAK3:SYK [plasma membrane] Hierarchy of protein tyrosine kinases in interleukin-2 (IL-2) signaling: activation of syk depends on Jak3; however, neither Syk nor Lck is required for IL-2-mediated STAT activation
[Reaction:451942] Within the IL-2R complex JAK3 phosphorylates JAK1 [Homo sapiens]
[Reaction:508282] SYK is a substrate for JAK1 [Homo sapiens] |
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No pathways have been reviewed or authored by Hierarchy of protein tyrosine kinases in interleukin-2 (IL-2) signaling: activation of syk depends on Jak3; however, neither Syk nor Lck is required for IL-2-mediated STAT activation (451930)
