Query author contributions in Reactome

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Details on Person Geahlen, RL

Class:Id	Person:451922
_displayName	Geahlen, RL
_timestamp	2010-01-14 16:52:48
created	[InstanceEdit:451938] Jupe, S, 2010-01-14
initial	RL
surname	Geahlen
(author)	[LiteratureReference:451930] Hierarchy of protein tyrosine kinases in interleukin-2 (IL-2) signaling: activation of syk depends on Jak3; however, neither Syk nor Lck is required for IL-2-mediated STAT activation [LiteratureReference:453173] Syk, activated by cross-linking the B-cell antigen receptor, localizes to the cytosol where it interacts with and phosphorylates alpha-tubulin on tyrosine [LiteratureReference:453191] Syk activation and dissociation from the B-cell antigen receptor is mediated by phosphorylation of tyrosine 130 [LiteratureReference:453202] Tyr130 phosphorylation triggers Syk release from antigen receptor by long-distance conformational uncoupling [LiteratureReference:508279] Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk [LiteratureReference:1861683] Identification of the major sites of autophosphorylation of the murine protein-tyrosine kinase Syk [LiteratureReference:1861717] Molecular basis for a direct interaction between the Syk protein-tyrosine kinase and phosphoinositide 3-kinase
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No pathways have been reviewed or authored by Geahlen, RL (451922)