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Details on Person Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID
| Class:Id | LiteratureReference:451897 |
| _displayName | Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID |
| _timestamp | 2010-01-14 16:46:14 |
| author | [Person:449955] Russell, SM [Person:451909] Johnston, JA [Person:166897] Noguchi, M [Person:451907] Kawamura, M [Person:451902] Bacon, CM [Person:451903] Friedmann, M [Person:451912] Berg, M [Person:210101] McVicar, DW [Person:207948] Witthuhn, BA [Person:207879] Silvennoinen, O |
| created | [InstanceEdit:451894] Jupe, S, 2010-01-14 |
| journal | Science |
| pages | 1042-5 |
| pubMedIdentifier | 7973658 |
| title | Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID |
| volume | 266 |
| year | 1994 |
| (literatureReference) | [Summation:1213491] Cytokine receptor common gamma subunit (IL2RG, IL-2 receptor... [Summation:6785855] Interleukin-4 (IL4) is a principal regulatory cytokine durin... [Summation:6789617] Janus kinase 3 (JAK3) binds constitutively to Interleukin-2 ... [Summation:9011746] Cytokine receptor common subunit gamma (IL2RG) binds Tyrosin... [Complex:8983163] IL2RG:JAK3 [endosome] [Homo sapiens] [Complex:8983189] IL2RB:JAK1 [endosome] [Homo sapiens] [Reaction:451900] IL2RB binds JAK1 [Homo sapiens] [Pathway:5602520] Gamma chain deficiency causes SCID [Homo sapiens] |
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