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Details on Person Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID

Class:IdLiteratureReference:451897
_displayNameInteraction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID
_timestamp2010-01-14 16:46:14
author[Person:449955] Russell, SM
[Person:451909] Johnston, JA
[Person:166897] Noguchi, M
[Person:451907] Kawamura, M
[Person:451902] Bacon, CM
[Person:451903] Friedmann, M
[Person:451912] Berg, M
[Person:210101] McVicar, DW
[Person:207948] Witthuhn, BA
[Person:207879] Silvennoinen, O
created[InstanceEdit:451894] Jupe, S, 2010-01-14
journalScience
pages1042-5
pubMedIdentifier7973658
titleInteraction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID
volume266
year1994
(literatureReference)[Summation:1213491] Cytokine receptor common gamma subunit (IL2RG, IL-2 receptor...
[Summation:6785855] Interleukin-4 (IL4) is a principal regulatory cytokine durin...
[Summation:6789617] Janus kinase 3 (JAK3) binds constitutively to Interleukin-2 ...
[Summation:9011746] Cytokine receptor common subunit gamma (IL2RG) binds Tyrosin...
[Complex:8983163] IL2RG:JAK3 [endosome] [Homo sapiens]
[Complex:8983189] IL2RB:JAK1 [endosome] [Homo sapiens]
[Reaction:451900] IL2RB binds JAK1 [Homo sapiens]
[Pathway:5602520] Gamma chain deficiency causes SCID [Homo sapiens]
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