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Details on Person Heterodimerization of nephrin and KIRREL2, KIRREL3

Class:Id	Reaction:451757
_displayName	Heterodimerization of nephrin and KIRREL2, KIRREL3
_doRelease	TRUE
_timestamp	2017-03-09 11:56:46
authored	[InstanceEdit:214881] de Bono, B, Garapati, P V, 2008-02-26 12:30:30
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:451754] Garapati, P V, 2010-01-11
edited	[InstanceEdit:532602] Garapati, P V, 2010-03-01
entityOnOtherCell	[EntityWithAccessionedSequence:197692] NPHS1-1 [plasma membrane] [Homo sapiens]
input	[Complex:373670] NPHS1 dimer [plasma membrane] [Homo sapiens] [DefinedSet:936056] KIRREL2, KIRREL3 [plasma membrane] [Homo sapiens]
literatureReference	[LiteratureReference:451747] NEPH2 is located at the glomerular slit diaphragm, interacts with nephrin and is cleaved from podocytes by metalloproteinases [LiteratureReference:936070] A model organism approach: defining the role of Neph proteins as regulators of neuron and kidney morphogenesis
modified	[InstanceEdit:451774] Garapati, P V, 2010-01-12 [InstanceEdit:532597] Garapati, P V, 2010-03-01 [InstanceEdit:765030] Garapati, P V, 2010-05-20 [InstanceEdit:847688] Garapati, P V, 2010-05-30 [InstanceEdit:933340] Garapati, P V, 2010-08-10 [InstanceEdit:936071] Garapati, P V, 2010-08-22 [InstanceEdit:2167920] Garapati, P V, 2012-03-23 [InstanceEdit:8981499] Jupe, Steve, 2017-03-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Heterodimerization of nephrin and KIRREL2, KIRREL3
output	[Complex:451719] NPHS1 dimer:KIRREL2,KIRREL3 [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:373732] Nephrin trans-homophilic interaction [Homo sapiens]
releaseDate	2010-09-21
reviewed	[InstanceEdit:765028] Huber, TB, Grahammer, Florian, 2010-05-20
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1104970] R-HSA-451757.3
summation	[Summation:451773] NEPH2 and NEPH3 specifically interact with the extracellular...
(hasEvent)	[Pathway:373753] Nephrin family interactions [Homo sapiens]
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No pathways have been reviewed or authored by Heterodimerization of nephrin and KIRREL2, KIRREL3 (451757)