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Details on Person Tpl2 phosphorylates Mek1, Sek1

Class:IdReaction:451681
_displayNameTpl2 phosphorylates Mek1, Sek1
_doReleaseTRUE
_timestamp2010-12-02 14:33:50
authored[InstanceEdit:744679] Ray, KP, 2010-05-17
catalystActivity[CatalystActivity:451669] MAP kinase kinase kinase activity of Tpl2 [cytosol]
catalystActivityReference[CatalystActivityReference:9643180] MAP kinase kinase kinase activity of Tpl2 [cytosol] Activation of MEK-1 and SEK-1 by Tpl-2 proto-oncoprotein, a novel MAP kinase kinase kinase
compartment[Compartment:70101] cytosol
created[InstanceEdit:451663] Jupe, S, 2010-01-08
edited[InstanceEdit:744688] Jupe, S, 2010-05-17
input[DefinedSet:451676] Mek1, Sek1 [cytosol] [Mus musculus]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
isChimericTRUE
literatureReference[LiteratureReference:451636] Activation of MEK-1 and SEK-1 by Tpl-2 proto-oncoprotein, a novel MAP kinase kinase kinase
modified[InstanceEdit:827362] Jupe, S, 2010-05-27
[InstanceEdit:9643047] Wu, G, 2019-04-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameTpl2 phosphorylates Mek1, Sek1
output[DefinedSet:451690] Phospho Mek1, Phospho Sek1 [cytosol] [Mus musculus]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
releaseDate2010-06-15
reviewed[InstanceEdit:744680] Pinteaux, E, 2010-05-17
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48892] Mus musculus
[Species:48895] Rattus norvegicus
stableIdentifier[StableIdentifier:1104410] R-NUL-451681.3
summation[Summation:451640] Tpl2 (also known as Cot, officially known as MAP3K8) is cons...
(inferredFrom)[Reaction:451649] TPL2 phosphorylates MEK1, SEK1 [Homo sapiens]
(updatedInstance)[_UpdateTracker:9779920] Update Tracker - [Reaction:451681] Tpl2 phosphorylates Mek1, Sek1 - v64:[modifyText]
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